Cytokines Flashcards
Source and function: IL-1
Macrophages
Acute Inflammation
Induces fever
COCKexia-1a
Source and function:
IL-2
Th1 Cells
Stimulates growth and differentiation of T cell response
IL2, 2 Cell Activation
Source and function:
IL-3
Activated T helper cells
Stimulates differentiation and proliferation of myeloid progenitor cells
3-some if you wanna bone
Source and function:
IL-4
Th2 cells
Stimulates proliferation and differentiation of B cells
Source and function:
IL-5
Th2 Cells
Stimulate production of eosinophils
5 fingers on a hand, eosinophils
Source and function:
IL-6
Macrophages, Th2 cells
Stimulates differentiation of B cells
Induces fever
Source and function:
IL-8
Macrophages
Neutrophil chemotaxis
8 on its side looks like infinity (neutrophils are the most superfluous cells)
Source and function:
IL-10
Th2 cells
Inhibits Th1 cytokine production
Also known as human cytokine synthesis inhibitory factor and is an ‘anti-inflammatory’ cytokine
Source and function:
IL-12
Dendritic cells, macrophages, B cells
Activates NK cells and stimulates differentiation of naive T cells into Th1 cells
Source and function:
TNF alpha
Macrophages
Induces fever
Neutrophil Chemotaxis
COCKexia 1 alpha
Source and function:
IFN Gamma
Th1 cells
Activates macrophages
Granuloma activation:Gamma
