tumour lysis syndrome

Question 1

define tumour lysis syndrome

Answer 1

Tumour Lysis Syndrome is a complication of chemotherapy treatment.

Question 2

what is tumour lysis syndrome caused by

Answer 2

This is an illness caused by the result of chemotherapy, where chemicals are released into the blood due to the destruction of cells.

Question 3

what does tumour lysis syndrome result in

Answer 3

• High uric acid
• High potassium
• High phosphate
• Low calcium (due to high phosphate)

Question 4

how does tumour lysis syndrome cause AKI

Answer 4

lead to uric acid crystals forming within the interstitial space
and tubules of the kidneys, causing AKI.

Question 5

complications associated with tumour lysis syndrome

Answer 5

• AKI
• cardiac arrest
• systemic inflammation

Question 6

how can tumour lysis syndrome cause cardiac arrests

Answer 6

because of hyperkaelamiea

Question 7

how can tumour lysis syndrome cause systemic inflammation

Answer 7

The release of cytokines

Question 8

how to prevent tumour lysis syndrome

Answer 8

very good hydration and good
urine output must be observed before chemotherapy patients start each
treatment.
Allopurinol or rasburicase may be used to suppress uric acid.