Tumors Flashcards
What is fibromatosis in palms called?
Dupoytren’s disease
What is fibromatosis in sole called?
Ladderhose’s disease
What is fibromatosis in penis called?
Pyronie’s disease
What is the most common soft tissue benign tumor in adults?
Lipoma
What is the most common soft tissue malignant tumor in adults?
Liposarcoma
What is the most common soft tissue tumor in children & adolescents ?
Rhabdomyosarcoma
IHC tests for rhabdomyosarcoma
1) Desmin
2) Myogenin
3) MYOD-1
IHC for synovial sarcoma
CK & EMA
Where does synovial sarcoma usually metastasize to usually?
Bones, lymph nodes and lungs
What soft tissues tumors could originate from the retroperitoneal ?
Liposarcoma, Fibrosarcoma and rhabdomyosarcoma
What kind of sun exposure causes SCC?
Cumulative
Which parts of the skin is melanoma usually found on?
Men’s upper backs
& Women’s legs
What type of sun exposure causes melanoma?
Intense Intermittent exposure at early age
What percentage of melanomas are familial?
5-10%
What organs does melanoma affect
Skin, mucus, eyes and meninges
Where do embryonic rhabdomyosarcomas develop?
Head, Neck & urogenital
Where do albeolar rhabdomyosarcomas develop?
Extremities of adolescents
Where do pleomorphic rhabdomyosarcomas develop?
Deep tissue of adults
Cell type found in rhabdomyosarcoma?
Strep/tadpole cells
Histology of high grade liposarcoma?
Myxoid stroma in grade 2
Pleomorphic & round cells in grade 3
Where does leiomyoma develop ?
Uterus and arrector pilli
Where does leiomyosarcoma develop ?
Uterus & deep extremities
Where does nodular fasciitis develop?
Upper extremity + trunk
Where does fibromatosis type B develop?
Abdomin, girdles & mesentery
Where does fibrosarcoma develop?
Deep tissue of thigh & knee
Age of synovial sarcoma patients?
20-50
Tumor cells in synovial sarcoma?
Spindle cells (& epithelial cells in biphasic)
Where does synovial sarcoma most likely develop?
Knee
Tumor cells in Dermatofibroma & dermatofibrosarcoma ?
Spindle cells & histiocytes
Tumor cells in UPS?
Bizarre spindle cells
Describe the lesion of actinic keratosis
Red scaly plaque with sand paper texture
Multiple BCC is associated with which disease?
Gorlin’s syndrome
What is leser trelat sign?
Multiple seborrheic keratosis on trunk indicating git carcinoma
Most common bone Ca in children?
Osteosarcoma
