Tumors Flashcards

1
Q

What is fibromatosis in palms called?

A

Dupoytren’s disease

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2
Q

What is fibromatosis in sole called?

A

Ladderhose’s disease

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3
Q

What is fibromatosis in penis called?

A

Pyronie’s disease

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4
Q

What is the most common soft tissue benign tumor in adults?

A

Lipoma

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5
Q

What is the most common soft tissue malignant tumor in adults?

A

Liposarcoma

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6
Q

What is the most common soft tissue tumor in children & adolescents ?

A

Rhabdomyosarcoma

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7
Q

IHC tests for rhabdomyosarcoma

A

1) Desmin
2) Myogenin
3) MYOD-1

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8
Q

IHC for synovial sarcoma

A

CK & EMA

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9
Q

Where does synovial sarcoma usually metastasize to usually?

A

Bones, lymph nodes and lungs

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10
Q

What soft tissues tumors could originate from the retroperitoneal ?

A

Liposarcoma, Fibrosarcoma and rhabdomyosarcoma

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11
Q

What kind of sun exposure causes SCC?

A

Cumulative

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12
Q

Which parts of the skin is melanoma usually found on?

A

Men’s upper backs
& Women’s legs

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13
Q

What type of sun exposure causes melanoma?

A

Intense Intermittent exposure at early age

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14
Q

What percentage of melanomas are familial?

A

5-10%

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15
Q

What organs does melanoma affect

A

Skin, mucus, eyes and meninges

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16
Q

Where do embryonic rhabdomyosarcomas develop?

A

Head, Neck & urogenital

17
Q

Where do albeolar rhabdomyosarcomas develop?

A

Extremities of adolescents

18
Q

Where do pleomorphic rhabdomyosarcomas develop?

A

Deep tissue of adults

19
Q

Cell type found in rhabdomyosarcoma?

A

Strep/tadpole cells

20
Q

Histology of high grade liposarcoma?

A

Myxoid stroma in grade 2
Pleomorphic & round cells in grade 3

21
Q

Where does leiomyoma develop ?

A

Uterus and arrector pilli

22
Q

Where does leiomyosarcoma develop ?

A

Uterus & deep extremities

23
Q

Where does nodular fasciitis develop?

A

Upper extremity + trunk

24
Q

Where does fibromatosis type B develop?

A

Abdomin, girdles & mesentery

25
Q

Where does fibrosarcoma develop?

A

Deep tissue of thigh & knee

26
Q

Age of synovial sarcoma patients?

A

20-50

27
Q

Tumor cells in synovial sarcoma?

A

Spindle cells (& epithelial cells in biphasic)

28
Q

Where does synovial sarcoma most likely develop?

A

Knee

29
Q

Tumor cells in Dermatofibroma & dermatofibrosarcoma ?

A

Spindle cells & histiocytes

30
Q

Tumor cells in UPS?

A

Bizarre spindle cells

31
Q

Describe the lesion of actinic keratosis

A

Red scaly plaque with sand paper texture

32
Q

Multiple BCC is associated with which disease?

A

Gorlin’s syndrome

33
Q

What is leser trelat sign?

A

Multiple seborrheic keratosis on trunk indicating git carcinoma

34
Q

Most common bone Ca in children?

A

Osteosarcoma