Pharma

Question 1

On which channel does succinylcholine work?

Answer 1

Sodium channel

Question 2

What is the depolarizing agent no longer used called?

Answer 2

Decamethonium

Question 3

How to choose between topical and systemic route for a skin disease?

Answer 3

Start with topical and move to systemic if disease doesn’t respond

Question 4

How to choose between oil-based and water-based vehicle for a topical treatment?

Answer 4

Water for acute, wet,thin
Oil for chronic,dry,thick

Question 5

What’s the difference between 1st and 3rd generation retinoids?

Answer 5

3rd generation doesn’t decrease sebum production

Question 6

What are the side effects common between topical drugs?

Answer 6

Peeling, dryness and irritation

Question 7

What is the most common oral acne antibiotic?

Answer 7

Minocycline

Question 8

What is the non-protein inhibitor antibiotic used topically for acne?

Answer 8

Dapsone

Question 9

What are the 3rd generation retinoids called and what are they used for?

Answer 9

Adapalene & Tazarotene ; 1st choice for comedonal and inflammatory acne

Question 10

Name the prophylaxis antibiotics used on skin injuries

Answer 10

Bacitracin (+) & Polymyxin B (-)

Question 11

Name the antibiotics used to treat skin infections

Answer 11

Mupirocin (+)
(Neo/Genta)mycin (-)

Question 12

What is Neosporin made of ?

Answer 12

Bacitracin + Polymyxin B + Neomycin

Question 13

What can we use for seborrheic dermatitis ?

Answer 13

Ciclopirox
1% shampoo for scalp
0.77% cream for face

Question 14

When are should acyclovir and pencyclovir best given?

Answer 14

Right before the onset of symptoms (eg. numbness)

Question 15

What causes pediculosis?

Answer 15

Lice

Question 16

Tachyphylaxis is a side effect of what topical drug?

Answer 16

Topical corticosteroids

Question 17

Name the antihistamine used for pruritis

Answer 17

Doxepin

Question 18

What can we use for severe pruritus?

Answer 18

Topical anesthesia (Pramoxin)

Question 19

What system does rheumatoid arthritis not affect?

Answer 19

CNS

Question 20

How fast should remission happen after diagnosis?

Answer 20

2 months

Question 21

Should rheumatoid arthritis patients exercise?

Answer 21

Yes but not during rheumatic crisis

Question 22

What time of the day should rheumatoid arthritis be given?

Answer 22

Morning

Question 23

What are the indications of corticosteroids used in rheumatoid arthritis?

Answer 23

1) bridging therapy
2) Severe arthritis even with DMARDs

Question 24

How can you protect the stomach from corticosteroids in rheumatoid treatment?

Answer 24

Give PPI (EXCEPT H2 BLOCKERS)

Question 25

Rheumatoid arthritis patient treated with Corticosteroids has joint swelling what could this be?

Answer 25

Treatment failure (many joints) Infection (one joint)

Question 26

What route of corticosteroids do we use for rheumatoid arthritis?

Answer 26

Oral, IV for severe and if it doesn’t work then IM

Question 27

What are the first NSAID, Corticosteroids and DMARDs you should try for RA?

Answer 27

Ibuprofen ; Prednisolone ; MTX

Question 28

How long does it take MTX to work?

Answer 28

6 months

Question 29

When is NSAID used for RA?

Answer 29

Starting monotherapy before confirming the diagnosis

Question 30

In what DMARDs should vaccine be given before treatment?

Answer 30

Rituximab & abatacept

Question 31

How long does it take for Methotrexate to start working?

Answer 31

6 months

Question 32

What DMARDs to use if MTX causes lung fibrosis ?

Answer 32

Leflunomide or azathioprine

Question 33

What to use for pregnant patient with RA?

Answer 33

Azathioprine Sulfasalazine TNF-a inhibitors Hydroxychloroquine

Question 34

What DMARDs to use for mild cases?

Answer 34

Hydroxychloroquine & Minocycline (antibiotics)

Question 35

What DMARDs should only be used in combination therapy and why?

Answer 35

Infliximab; prevent Ab development & allergic reaction

Question 36

Which jak inhibitor is not a DMARD?

Answer 36

Tofacitinib

Question 37

What mnemonic can be used for memorizing Biological DMARDs?

Answer 37

TNF-a ; sister.lizzie intercepts In Adil’s Goals Non-TNF-a; Talk-to-lizzie (in) Ankara about-accepting Rital (Adil’s wife)