Tumor Markers Flashcards
CEA
Carcinoembryonic antigen (non-specific; produced by about 70% of colorectal and pancreatic cancers; also produced by gastric, breast, and thyroid medullary carcinomas)
a-fetoprotein
Hepatocellular carcinomas
Nonseminomatous germ cell tumor of testis (i.e. yolk sac tumor)
b-HCG
H - hydatidiform moles
C - choriocarcinomas
G - Gestational trophoblastic tumors
CA-125
Ovarian, malignant epithelial tumors
S-100
Melanoma, neural tumors, schwannomas
Alkaline phosphatase
Metastases to bone, obstructive biliary disease, Paget’s disease of bone
Bombesin
Neuroblastoma, lung/gastric cancer
TRAP (tartrate-resistant acid phosphatase)
Hairy cell leukemia (a Bcell neoplasm)
CA-19-9
Pancreatic adenocarcinoma
Calcitonin
Thyroid medullary carcinoma