Chemical Carcinogens - Oncogenic Viruses Flashcards
Aflatoxins (organ and impact)
Organ: Liver
Impact: Hepatocellular carcinoma
Vinyl chloride (organ and impact)
Organ: Liver
Impact: Angiosarcoma
CCl4 (organ and impact)
Organ: Liver
Impact: Centrilobular necrosis/fatty change
Nitrosamines (smoked foods - organ and impact)
Organ: Stomach
Impact: Gastric cancer
Cigarette smoke (organ - larynx; and impact)
Organ: Larynx
Impact: Squamous cell carcinoma
Cigarette smoke (organ - lung; and impact)
Organ: Lung
Impact: Squamous cell and small cell carcinoma
Cigarette smoke (organ - kidney; and impact)
Organ: Kidney
Impact: Renal cell carcinoma
Cigarette smoke (organ - bladder; and impact)
Organ: Bladder
Impact: Transitional cell carcinoma
Asbestos (organ and impact)
Organ: Lung
Impact: Mesothelioma and bronchogenic carcinoma
Arsenic (organ - skin; and impact)
Organ: Skin
Impact: Squamous cell carcinoma
Arsenic (organ - liver; and impact)
Organ: Liver
Impact: Angiosarcoma
Naphthalene (aniline) dyes - organ and impact
Organ: Bladder
Impact: Transitional cell carcinoma
Alkylating agents (organ and impact)
Organ: Blood
Impact: Leukemia
Hepatocellular carincoma
Aflatoxins
Angiosarcoma of the liver
1 - Vinyl chloride
2 - Arsenic
Centrilobular necrosis and fatty changes
CCl4
Gastric cancer
Nitrosamines
Squamous cell carcinoma of the larynx
Cigarette smoke
Squamous cell/small cell carcinoma of lung
Cigarette smoke
Renal cell carcinoma
Cigarette smoke
Transitional cell carcinoma of the bladder
1 - Cigarette smoke
2 - Naphthalene (aniline) dyes
Mesothelioma
Asbestos
Bronchogenic carcinoma
Asbestos
Squamous cell carcinoma of the skin
Arsenic
Leukemia
Alkylating agents
EBV
Nasopharyngeal carcinoma, Burkitt lymphoma, CNS lymphoma in AIDS
HHV-8
Kaposi sarcoma
HBV/HCV
Hepatocellular carcinoma
HTLV-1
Adult T-cell leukemia/lymphoma
HPV 16, 18, 31, 33
Squamous cell carcinoma of vulva, vagina, anus and cervix; adenocarcinoma of cervix
Virus associated with nasopharyngeal carcinoma
EBV
Virus associated with Burkitt’s lymphoma
EBV
Virus associated with CNS lymphoma in AIDS
EBV
Virus associated with Kaposi sarcoma
HHV-8
Virus associated with Hepatocellular carcinoma
HBV/HCV
Virus associated with Adult T-cell leukemia/lymphoma
HTLV-1
Virus associated with Squamous cell carcinoma of vulva, vagina, anus and cervix
HPV subtypes 16, 18, 31, 33