Tumor markers Flashcards

1
Q

Alk phos

A

Met to bones, liver,
Paget disease of bone
Seminoma (placental ALP)

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2
Q

alpha fetoprotein

A
HCC
Hepatoblastoma
Yolk sac (endodermal sinus)
Testicular cancer
Mixed germ cell tumor (co secreted with beta hCG)
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3
Q

beta hCG

A

Hydatidiform mole
choriocarcinoma (gestational trophoblastic disease)
TEsticular cancer

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4
Q

CA-15-3/CA-27-29

A

Breast Ca

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5
Q

CA-19-9

A

Pancreatic

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6
Q

CA-125

A

Ovarian cancer

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7
Q

Calcitonin

A

Medullary thryoid carcinoma

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8
Q

CEA

A

Carcino Embrynoic antigen
Nonspecific but produced by colorectal and pancreatic cancers
Also produced by gastric breast, and medullary thyroid carcinoma

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9
Q

S100

A

Neural crest origin

Melanoma, neural tumors, schwannomas, Langerhans cells histiocytosis

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10
Q

TRAP

A

Tartrate Resistant Acid Phosphate (TRAP)

Hairy cell leukemia

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