Auto antibodies Flashcards

1
Q

anti nuclear antibodies ANA

A

SLE, nonspecific

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2
Q

Anti dsDNA, anti smith

A

SLE

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3
Q

Antihistone

A

Drug induced lupus

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4
Q

RA, anti CCP

A

Rheumatoid factor

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5
Q

Anti centromere

A

Scleroderma (CREST syndrome)

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6
Q

Anti Scl-70 (anti DNA topo I)

A

Scleroderma (diffuse)

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7
Q

Anti mitochondrial

A

primary biliary cirrhosis

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8
Q

IgA antiendomysial, IgA anti tissue transglutaminase

A

Celiac disease

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9
Q

Anti basement membrane

A

Goodpasture’s syndrome

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10
Q

Anti desmolegin

A

Pemphigus vulgaris

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11
Q

Anti microsomal, antithyroglobulin

A

Hashimotos thyroiditis

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12
Q

Anti Jo-1, anti SRP, anti Mi-2

A

Polymyositis, dermatomyositis

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13
Q

Anti SSA (anti Ro)

A

Sjogren’s

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14
Q

Anti SSB (anti La)

A

Sjogren’s

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15
Q

Anti U1 RNP

A

Mixed connective tissue disease

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16
Q

Anti smooth muscle

A

autoimmune hepatitis

17
Q

Anti glutamate decarboxylase

A

Type I diabetes mellitus

18
Q

c-ANCA

A

Granulomatosis with polyangiitis (Wegener’s)

19
Q

p-ANCA

A

Microscopic polyangiitis, Churg-Strauss syndrome