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Pathology > Tumor markers > Flashcards

Tumor markers Flashcards

1
Q

PSA

A

Any prostate pathology

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2
Q

Prostatic acid phosphatase

A

Prostate carcinoma

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3
Q

CEA (carinoembryonic antigen)

A

Non-specific but 70% of colorectal and pancreatic cancers. Also gastric, breast, medullary thyroid cancers.

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4
Q

alpha- fetoprotein

A

HCC, Nonseminomatous germ cell tumors of testis and ovary (namely Yolk sac carcinoma aka endodermal sinus tumor)

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5
Q

beta-hCG

A

Hydatidiform moles -> Choriocarcioma = Gestational trophoblastic disease (HCG!)

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6
Q

CA-125

A

Ovarian cancer (but not a good screening test)

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7
Q

S-100

A

Melanoma, Astrocytoma, Neural tumors, Schwannomas (MANS S-100)

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8
Q

Alkaline Phosphatase

A

Mets to bone, biliary disease, paget’s disease of bone

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9
Q

Bombesin

A

Neuroblastoma (adrenal), lung and gastric cancer

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10
Q

TRAP

A

Hairy cell leukemia (B-cells)

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11
Q

CA-19-9

A

Pancreatic adenocarcinoma

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12
Q

Calcitonin

A

Medullary thyroid cancer

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Pathology (8 decks)

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