Tuberculosis Detection and Control Flashcards
what is the causative agent of TB?
mycobacterium tuberculosis
describe tubercle bacilli
slender, rod-shaped bacterium
non-motile
strictly aerobic
what system does TB usually attack
lungs (pulmonary TB)
how is TB spread?
airborne by droplet nuclei
what is the reservoir of TB?
ONLY humans
what are the two stages of TB?
latent/dormant TB
active disease
describe latent/dormant TB stage
infection can be given treatment to prevent the possible progression of disease
inactive, bacteria not multiplying
no symptoms
not infectious
not a case of TB
describe the active disease stage
active, bacteria multiplying
symptoms, infectious, a case of TB
what are some pulmonary symptoms of TB
chronic cough
chest pain
hemoptysis
what are some systemic symptoms of TB
fatigue
malaise
fever
what are some risk factors of active TB?
HIV infection
overcrowding/malnutrition
recent TB infection
foreign born
what are the two types of TB tests?
skin test (TST)
blood test (IGRA)
isoniazid toxicity
drug-induced hepatitis: prevents normal function of liver
signs/Sx of isoniazid toxicity
hepatitis (most dangerous side effect)
tingling of hands/feet
multi-drug resistant TB (MDR-TB)
dangerous form of TB that results in resistance to first line medications