Rabies Control Program Management

Question 1

rabies

Answer 1

affects the CNS
causes encephalopathy/death

Question 2

reservoir of rabies

Answer 2

wild/domesticated mammals

Question 3

modes of transmission (rabies)

Answer 3

contact of saliva

Question 4

incubation (rabies)

Answer 4

3-8 weeks

Question 5

period of communicability

Answer 5

time during which infection may be transmitted directly/indirectly

Question 6

period of communicability for domestic animals

Answer 6

3-5 days before clinical signs/Sx

Question 7

stage 1

Answer 7

no clinical signs of illness

Question 8

stage 2 (prodrome)

Answer 8

1st signs of clinical symptoms
Sx last 2-10 days

Question 9

stage 3 (acute neurological)

Answer 9

hyperactivity, excitability, increased salivation
hydrophobia
2-7 days, ends w/ coma

Question 10

stage 4 (coma)

Answer 10

last up to 14 days

Question 11

stage 5

Answer 11

death or recovery occurs
survival is rare

Question 12

Sx for animals

Answer 12

nonspecific
signs progress to neurological effects
death within 7 days

Question 13

diagnosis (humans)

Answer 13

saliva
serum/spinal fluid
skin biopsies

Question 14

diagnosis (animals)

Answer 14

brain tissue (euthanized)

Question 15

Tx (humans)

Answer 15

Clean wound
Post-Exposure Prophylaxis (PEP):
Human Rabies Immune Globulin (HRIG)- passive immunity
Human Diploid Cell Vaccine (HDCV)- active immunity
Tx has to be given before Sx show

Question 16

when are the doses for HDCV given?

Answer 16

days 0, 3, 7, 14
if patient is immunocompromised: 5th vaccine given on 28th day

Question 17

Tx (animals)

Answer 17

no treatment
vaccinated animals: home quarantined 45 days
unvaccinated animals: euthanasia

Question 18

prevention (rabies)

Answer 18

education
quarantine
animal control
pre-exposure vaccination

Question 19

References

Answer 19

AFI 48-105 (PH Surveillance)
AFI 48-131 (Vet Health Services)
DD form 2341