Tuberculosis Flashcards

1
Q

Describe the etiology of TB

A

primary, primary progressive, latent, secondary forms

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2
Q

Describe the primary immune response to TB

A
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3
Q

Describe the clinical presentation of primary TB

A
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4
Q

Describe the clinical presentation of primary progressive TB

A
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5
Q

Describe the clinical presentation of latent TB

A

asymptomatic

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6
Q

Describe the clinical presentation of secondary TB

A
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7
Q

Describe the diagnostic testing for TB

A
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8
Q

Describe the treatment of TB

A

Many regimens for LTBI, intensive & continuation phases for active pulmonary TB, peds should get short course under DOTs

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9
Q

Describe Miliary TB

A
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10
Q

When is PZA contraindicated

A

in severe liver dz, gout, and pregnancy

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11
Q

Describe the etiology of extrapulmonary TB

A
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12
Q

Describe the etiology of pediatric TB

A
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13
Q

Describe the etiology/types of drug resistant TB

A
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14
Q

Describe the clinical presentation of pediatric TB

A
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15
Q

Describe the diagnostic testing for pediatric TB

A
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16
Q

Describe some ways to improve adherence to TB treatment

A
  • DOT clinics
  • multidrug combo therapy
  • pt education
  • incentives
  • hospitalization
17
Q

Describe the Four I’s of TB prevention

A
  • intensive case findings
  • INH
  • Isolation
  • Immunization (BCG)
18
Q

When will a TST be positive after exposure/primary immune response to TB

A

8-12 weeks

19
Q

Describe the criteria for TST positivity

20
Q

List the main adverse effects of rifampin

21
Q

What are the main adverse effects for isoniazid

22
Q

Describe the main adverse effects for pyrazinamide

23
Q

What is the main adverse effect for ethambutol

A

optic neuritis

24
Q

Describe the main adverse effects for streptomycin

25
Can you give the BCG vaccination in pregnancy
no, CI in pregnancy
26
Can you give the BCG vaccination in LTBI
no, they already have dormant organisms (may or may not reactivate)