Tuberculosis Flashcards
Describe the etiology of TB
primary, primary progressive, latent, secondary forms
Describe the primary immune response to TB
Describe the clinical presentation of primary TB
Describe the clinical presentation of primary progressive TB
Describe the clinical presentation of latent TB
asymptomatic
Describe the clinical presentation of secondary TB
Describe the diagnostic testing for TB
Describe the treatment of TB
Many regimens for LTBI, intensive & continuation phases for active pulmonary TB, peds should get short course under DOTs
Describe Miliary TB
When is PZA contraindicated
in severe liver dz, gout, and pregnancy
Describe the etiology of extrapulmonary TB
Describe the etiology of pediatric TB
Describe the etiology/types of drug resistant TB
Describe the clinical presentation of pediatric TB
Describe the diagnostic testing for pediatric TB
Describe some ways to improve adherence to TB treatment
- DOT clinics
- multidrug combo therapy
- pt education
- incentives
- hospitalization
Describe the Four I’s of TB prevention
- intensive case findings
- INH
- Isolation
- Immunization (BCG)
When will a TST be positive after exposure/primary immune response to TB
8-12 weeks
Describe the criteria for TST positivity
List the main adverse effects of rifampin
What are the main adverse effects for isoniazid
Describe the main adverse effects for pyrazinamide
What is the main adverse effect for ethambutol
optic neuritis
Describe the main adverse effects for streptomycin
Can you give the BCG vaccination in pregnancy
no, CI in pregnancy
Can you give the BCG vaccination in LTBI
no, they already have dormant organisms (may or may not reactivate)
