Tuberculosis Flashcards

1
Q

Describe the etiology of TB

A

primary, primary progressive, latent, secondary forms

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2
Q

Describe the primary immune response to TB

A
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3
Q

Describe the clinical presentation of primary TB

A
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4
Q

Describe the clinical presentation of primary progressive TB

A
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5
Q

Describe the clinical presentation of latent TB

A

asymptomatic

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6
Q

Describe the clinical presentation of secondary TB

A
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7
Q

Describe the diagnostic testing for TB

A
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8
Q

Describe the treatment of TB

A

Many regimens for LTBI, intensive & continuation phases for active pulmonary TB, peds should get short course under DOTs

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9
Q

Describe Miliary TB

A
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10
Q

When is PZA contraindicated

A

in severe liver dz, gout, and pregnancy

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11
Q

Describe the etiology of extrapulmonary TB

A
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12
Q

Describe the etiology of pediatric TB

A
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13
Q

Describe the etiology/types of drug resistant TB

A
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14
Q

Describe the clinical presentation of pediatric TB

A
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15
Q

Describe the diagnostic testing for pediatric TB

A
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16
Q

Describe some ways to improve adherence to TB treatment

A
  • DOT clinics
  • multidrug combo therapy
  • pt education
  • incentives
  • hospitalization
17
Q

Describe the Four I’s of TB prevention

A
  • intensive case findings
  • INH
  • Isolation
  • Immunization (BCG)
18
Q

When will a TST be positive after exposure/primary immune response to TB

A

8-12 weeks

19
Q

Describe the criteria for TST positivity

A
20
Q

List the main adverse effects of rifampin

A
21
Q

What are the main adverse effects for isoniazid

A
22
Q

Describe the main adverse effects for pyrazinamide

A
23
Q

What is the main adverse effect for ethambutol

A

optic neuritis

24
Q

Describe the main adverse effects for streptomycin

A
25
Q

Can you give the BCG vaccination in pregnancy

A

no, CI in pregnancy

26
Q

Can you give the BCG vaccination in LTBI

A

no, they already have dormant organisms (may or may not reactivate)