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Pulm Pharm Flashcards

1
Q

List some albuterol rescue inhalers

A

ProAir, Proventil, Ventolin

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2
Q

List an ICS/SABA inhaler

A

Airsupra (Budesonide/Albuterol)

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3
Q

What are ICS/SABA inhalers used for

A

asthma relief

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4
Q

List some SABA nebulizer solutions

A

albuterol sulfate & levalbuterol HCl

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5
Q

List 4 ICS/LABA inhalers

A

Symbicort (Budesonide/Formoterol)

Dulera (Mometasone/Formoterol)

Advair Diskus/HFA (Fluticasone/Salmeterol)

Breo Ellipta (Fluticasone/Vilanterol)

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6
Q

List 2 LABA inhalers for COPD

A

Striverdi Respimat (Olodaterol)

Servent Diskus (Salmeterol)

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7
Q

List 2 LABA nebulizer solutions for COPD

A

Brovana (Aformoterol) & Perforomist (Formoterol)

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8
Q

List one SAMA inhaler

A

Atrovent HFA (Ipratropium)

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9
Q

List a SAMA/SABA inhaler

A

Combivent Respimat (Ipratroprium/Albuterol)

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10
Q

List a SAMA/SABA nebulizer solutions

A

Ipratropium Bromide (DuoNeb)

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11
Q

List 2 LAMA inhalers

A

Spiriva Handihaler/Respimat (Tiotropium)

Incruse Ellipta (Umeclidinium)

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12
Q

List some ICS inhalers

A
  • Beclomethasone HFA (Qvar RediHaler)
  • Budesonide DPI (Pulmicort Flexhaler)
  • Ciclesonide HFA (Alvesco)
  • Fluticasone Proprionate HFA (Flovent HFA)
  • Fluticasone Propionate DPI (Armonair Digihaler)
  • Fluticasone Furoate DPI (Arnuity Ellipta)
  • Mometasone DPI (Asmanex Twisthaler)
  • Mometasone HFA (Asmanex HFA)
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13
Q

List 3 LABA/LAMA inhalers

A
  • Stiolto Respimat (Olodaterol/Tiotropium)
  • Anoro Ellipta (vilanterol/umeclidinium)
  • Bevespi (Formoterol fumarate/glycopyrolate)
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14
Q

List 2 ICS/LABA/LAMA inhalers

A
  • Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol)
  • Breztri Aerosphere (Budesonide/Glycopyrolate/Formoterol)
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15
Q

List one leukotriene inhibitor

A

Montelukast (Singulair) PO

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16
Q

List the core TB drugs

A

RIPE-s

R: Rifampin
I: Isonazid
P: Pyrazinamide
E: Ethambutol
S: Streptomycin (IV)

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17
Q

List some AEs of SABAs and LABAs

A

tachycardia, muscle tremor, hypokalemia, restlessness, metabolic effects

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18
Q

What are SABAs used for

A
  • acute asthma/COPD exacerbations
  • PRN usage
  • preventative usage

albuterol, levalbuterol, fenoterol

19
Q

What are LABAs used for

A
  • scheduled maintenance for asthma/COPD
  • best used in combo with ICS or LAMA

formoterol, salmeterol, oladaterol

20
Q

What are SAMAs used for

A
  • combo with albuterol as a rescue inhaler or for exacerbations
  • can use 3-4x daily for COPD
  • PRN monotherapy NOT recommended d/t longer onset

ipratropium bromide

21
Q

What are LAMAs used for

A
  • drug of choice for COPD
  • can increase FEV and decrease moderate exacerbations
  • can also be used for asthma

tiotropium, umeclidinium

22
Q

What are some AEs of SAMAs & LAMAs

A
  • small rebound increase in airway responsiveness, dry mouth, bitter taste, urinary retention in older pts
23
Q

What are ICSs used for

A
  • first line for persistent asthma in combo with SABA or LABA
  • add-on for COPD

Fluticasone propionate/furoate, beclometasone, mometasone, budesonide

24
Q

What are some AEs of ICSs

A

pharyngitis, thrush, hoarseness, increased IOP, pituitary axis suppression, growth deceleration

25
What are ICS/SABAs used for
asthma reliever PRN (budesonide/albuterol)
26
What are ICS/LABAs used for
rescue or maintenance for COPD & asthma (symbicort, dulera, breo ellipta)
27
What are ICS/LABA/LAMA used for
- cut back on meds for COPD patients - also approved for asthma (trelegy ellipta, breztiri aerosphere)
28
What are leukotriene inhibitors used for
- daily asthma treatment - best for pts with allergies (montelukast)
29
What is the BBW for montelukast
neuropsychiatric effects
30
What is Dupixent used for
moderate to severe eosinophilic asthma and in patients 6+
31
What is Xolair used for
moderate to severe persistent asthma
32
What are some AEs of dupixent and xolair
Dupixent: injection site rxn, transient eosinophilia, psoriasis risk Xolair: hypersensitivity, anaphylaxis, urticaria, injection site rxn, possible CVD risk
33
List the monotherapy treatment of choice for CAP with no risk factors or allergies
Levofloxacin (FQ) OR OMadacycline (tetra) OR Lefamulin (pleuromutalin)
34
List the combo regimen for CAP (pneumococcal and atypical coverage)
**Anti-pneumococcal** - ampicillin sulbactam (PCN) - amoxicillin (PCN) - ceftriaxone (3rd G ceph) - cefotaxime (3rd G ceph) - ertapenem (carbapenem) **Atypical** - azithromycin (macrolide) - doxycycline (tetracycline)
35
List the monotherapy CAP regimen with MRSA coverage
**CAP mono:** Levofloxacin or moxifloxacin (FQs) **MRSA:** Vancomycin (lipo/glycopeptide) or Linezolid (oxazolidinone)
36
List the combo therapy for CAP with MRSA coverage
**Combo:** - Ampicillin-sulbactam (PCN) **OR** ceftriaxone (3 ceph) **OR** cefotaxime (3 ceph) **OR** Ertapenem (carb) - azithromycin (macro) **OR** doxycycline (tetra) **MRSA** - vancomycin (lipo/glyco) **OR** linezolid (oxazolid)
37
List the therapy for CAP with pseudomonal coverage
**antipneumococcal, antipseudomonal beta-lactam** - pip-tazo (PCN) **OR** cefepime (4 ceph) **OR** ceftazidime (3 ceph) **OR** meropenem (carb) **antipseudomonal** - ciprofloxacin **OR** levofloxacin (FQs)
38
List the treatment for CAP with MRSA and pseudomonal coverage
**antipneumococcal, antipseudomonal beta-lactam** - pip-tazo (PCN) **OR** cefepime (4 ceph) **OR** ceftazidime (3 ceph) **OR** meropenem (carb) **antipseudomonal** - ciprofloxacin **OR** levofloxacin (FQs) **MRSA** - vancomycin (lipo/glyco) **OR** linezolid (oxazolid)
39
What should you give for CAP with a beta-lactam allergy and NO other risk factors
levofloxacin (FQ) (no aztreonam)
40
What should you give for CAP with a beta-lactam allergy AND MRSA risk
vancomycin **OR** Linezolid
41
What should you give for CAP with a beta-lactam allergy AND pseudomonas risk
One aminoglycoside (Tobramycin, gentamicin, amikacin) **AND** aztreonam (monobactam)
42
What should be given for CAP with a beta-lactam allergy AND risk of both pseudomonas and MRSA
CAP: aztreonam & levofloxacin **AND** MRSA: Vancomycin OR linezolid **AND** Pseudomonas: Tobramycin OR gentamicin OR amikacin
43
What is standard coverage for hospital acquired pneumonia
Standard coverage: Pip-tazo (PCN) and/or cefepime (4th ceph) Gram-RFs: imipenem or meropenem Carbapenem resistance hx: ceftazidime-avibactam OR ceftolozane-tazobactam OR iminpenem-cilistatin-relebactam OR meropenem-vaborbactam

Pulmonology (19 decks)

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