Tuberculosis Flashcards

1
Q

Estudio inicial en TB activa

A

Baciloscopía seriada

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2
Q

Estudio inicial en TB latente

A

PPD

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3
Q

Estudio inicial en TB activa + VIH

A

Grnexpert MTB/RIF

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4
Q

Estudio inicial en TB activa y VIH

A

PPD

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5
Q

Enfermedad asociad mayormente a TB

A

Diabetes

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6
Q

Incidenci TB

A

1.28 por cada 1000 habitantes

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7
Q

Tx TB

A

Isoniazida
Rifampicina
Estreptomicina
Etambutol

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8
Q

No. De Dosis que incluyefase intensiva tx TB

A

60 dosis
Lunes a sábado: 10 semanas

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9
Q

No. De dosis que incluye fase de sosten tx TB

A

45 dosis
Lunes Miércoles viernes:15 semanas

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10
Q

Duración tx TB pulmonar

A

6 meses

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11
Q

Duración tx TB menkngea

A

12 meses

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12
Q

Dursción tx TB osea

A

9 meses

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13
Q

Principal efecto adverso Isoniazida

A

Neuropatía periferica

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14
Q

Como evitas efecto por isoniazida adverso

A

Con pirodixina (B6)

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15
Q

Efwcto adverso por etambutol

A

Neuritis oprica (rojo-verde)

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16
Q

Efecto adverso por Pirazinamida

A

Hipeuricemia

17
Q

Efecto adverso por rifampicina

A

Hepatotoxicidad

18
Q

Tamaño de PPD en TB latente

A

> 5 mm

19
Q

Quimioprofilaxis en TB latente

A

Isoniazida x 6 meses
5-10 mg/kg/dia

20
Q

A quienes dar profilaxis para TB

A

Contactos <5 años con o sin BCG, 5-14 años sin BCG, >15 años inmunosuprimidos y VIH a cualquier edad

21
Q

Tx en recaídas de TB

A

Estreptomicina
Isoniazida
Rifampicina
Etambutil
Pirazinamida
Por 8 meses

22
Q

Inhibe enzima arabino-transferasa

A

Etambutol

23
Q

Inhibe RNA polimerasa

A

Rifampicina

24
Q

Inhibe acidos nucleicos micolicos

A

Isoniazida