Leucemia Linfocítica Crónica Flashcards

1
Q

Supervivencia LLC

A

10 años

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2
Q

Factores riesgo LLC

A

Ant. Fam
Bencenos
Solventes
Radiación

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3
Q

Clinica LLC

A

Tríada:
Linfadenopatía
Hepatoesplenomegalia
Linfocitos >5000/uL por 3 meses (anemia/pérdida de peso)

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4
Q

Dx de LLC

A

Bh con linfocitosis
Aspirado de medula osea con >30% linfocitos maduros

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5
Q

Inmunotipos de LLC

A

CD5
CD19
CD20
CD21

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6
Q

Alteración genetica LLC

A

Deleción cromosoma 13q

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7
Q

En qué casos dar tx para LLC

A

Sintomatico, anemia, trombocitopenia y sx de Ritcher, Rai III o Biner C

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8
Q

Tratamiento para leucmina linfocítica crónica

A

Fudarabina + ciclofosfamida + rituximab o clorambucilo si >60 años o comorbidos

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