Tropical Diseases

Question 1

Pathogen and virulence factor? Typhoid / enteric fever

Answer 1

Salmonella Typhi and Paratyphi
Gram negative endotoxin
Fimbraie - lymphoid adhesion

Question 2

Where is Typhoid / enteric fever found and how is it spread?

Answer 2

Asia
Poor sanitation
Fecal - oral route

Question 3

Symptoms and incubation period? Typhoid / enteric fever

Answer 3

Fever, headache, GI, cough

14 days incubation

Question 4

Investigations and treatment? Typhoid/ enteric fever

Answer 4

Blood culture and LFT

Fluroquinolones Ceftriaxone

Question 5

Story? Dengue fever

Answer 5

Young traveller 
Fever
Headache
Normal observations
Maculopapular rash (flat, red, widespread)

Question 6

Transmission and incubation? Dengue fever

Answer 6

Vector - day biting

1 week incubation

Question 7

Investigations and treatment? Dengue fever

Answer 7

PCR / ELISA / serology to confirm

Supportive treatment only

Question 8

How is Ebola spread and how do you die from it?

Answer 8

Body fluids

Bleeding - shock

Question 9

What is the main risk with Zika virus?

Answer 9

Pregnancy - risk of fetal neurological damage

Question 10

What is Katayama / Schistosomiastis known as? Where is it found and how doe it infect?

Answer 10

Swimmer’s foot
Fresh water lakes
Worm gives an egg, which infects a human, some eggs are released in the sufferer’s faeces, and the cycle starts again