EBV Flashcards
1
Q
Patient? EBV
A
Teenager Fever Pharyngitis Enlarged lymph nodes Jaundice Rash
2
Q
How does EBV enter and infect the body?
A
Intimate contact with saliva
Infects epithelial cells of oropharynx
Infects B cells - latency, then they proliferate and activate T cells
Increased amount of IgG, IgM, IgA
High T / B cell count = enlarged liver, spleen, lymph nodes
3
Q
What is EBV also known as?
A
Infectious mononucleosis
Glandular fever
4
Q
What cancers are EBV associated with?
A
Stomach cancer
Hodgkin’ lymphoma - UK
Burkett’s lymphoma - developing countries
5
Q
Investigations? EBV
A
FBC
PCR
EBV antibodies
6
Q
Treatment? EBV
A
Acyclovir - anti viral
NOT amoxicillin - rash in EBV patients
