Haemophilia Influenzae Flashcards

1
Q

Story? Haem Inf

A

Adult with flu like symptoms - ear infection, sinusitis, pneumonia - contagious spread

Rarer - Young infant with cellulitis, or adult with cellulitis - disseminated spread

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2
Q

Transmission? Haem Inf

A

Respiratory droplets or disseminated spread

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3
Q

Pathogen? Haem Inf

A

Gram neg bacilli

Capsulated or uncapsulated

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4
Q

Where in body normally found? Haem Inf

A

Normal flora of upper respiratory tract

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5
Q

Virulence factors? Haem Inf

A

Capsule - protection
Endotoxin - LPS
IgA protease - degrades IgA so can enter bloodstream

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6
Q

Investigations? Haem Inf

A
Chocolate agar (not blood)
ELISA if capsular
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7
Q

Treatment? Haem Inf

A

Prevention - vaccine, PPP
Standard - Ampicillin if not life threatening
Meningitis - Ceftriaxone
Relatives if meningitis - Rifampin (precaution)

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