Haemophilia Influenzae Flashcards
1
Q
Story? Haem Inf
A
Adult with flu like symptoms - ear infection, sinusitis, pneumonia - contagious spread
Rarer - Young infant with cellulitis, or adult with cellulitis - disseminated spread
2
Q
Transmission? Haem Inf
A
Respiratory droplets or disseminated spread
3
Q
Pathogen? Haem Inf
A
Gram neg bacilli
Capsulated or uncapsulated
4
Q
Where in body normally found? Haem Inf
A
Normal flora of upper respiratory tract
5
Q
Virulence factors? Haem Inf
A
Capsule - protection
Endotoxin - LPS
IgA protease - degrades IgA so can enter bloodstream
6
Q
Investigations? Haem Inf
A
Chocolate agar (not blood) ELISA if capsular
7
Q
Treatment? Haem Inf
A
Prevention - vaccine, PPP
Standard - Ampicillin if not life threatening
Meningitis - Ceftriaxone
Relatives if meningitis - Rifampin (precaution)