Streptococcus Pyogenes

Question 1

Story? Strep Pyo

Answer 1

Child with sore throat

Fever, head ache, lymphoid hyperplasia, tonsillopharyngeal exudates

Question 2

3 complications from streptococcus induced sore throat?

Answer 2

Peritonsillar abscess
Scarlet fever - widespread rash, fever, sepsis
Acute Rheumatic fever - inflammation of heart, joints, CNS, valves

Question 3

Name 5 skin infections associated with Streptococcus Pyogenes?

Answer 3

Impetigo, Erysipelas, Cellulitis, Necrotising fasciitis, Streptococcal toxic shock syndrome

Question 4

What is cellulitis?

Answer 4

Skin and subcutaneous tissue infection

Impaired lympathic drainage - swelling

Question 5

What is necrotising fasciitis?

Answer 5

When cellulitis spreads to fascia
Rapid onset
High mortality
Necrosis

Question 6

What is Erysipelas?

Answer 6

A dermis infection affecting the face and lower limbs in adults.
Raised ridge to rash.

Question 7

Transmission? Strep Pyo

Answer 7

Droplets - inhalation

Question 8

Bacteria? Strep Pyo

Answer 8

Gram pos cocci

Beta haemolysis

Question 9

Where normally found? Strep Pyo

Answer 9

Pharyngeal mucosa

Question 10

Virulence factors? Strep Pyo

Answer 10

M proteins on surface of bacteria - resistant to phagocytosis
- inflammatory response
Streptokinase - dissolution of clots from plasminogen and plasmin

Question 11

Treatment? Strep Pyo

Answer 11

Penicillin G

Question 12

Investigations? Strep Pyo

Answer 12

Throat / pus swabs

Sugar agar