Triptans- Migraines Flashcards
1
Q
Drug Names
A
Eletriptan
Sumatriptan
Zolmitriptan
2
Q
MOA
A
Cause cranial vascular constriction and relief of migraine
Bind to selective serotonin receptor sites to cause vasoconstriction of cranial vessels
3
Q
Indication
A
Treatment of acute migraine are not used for prevention
4
Q
Contraindications
A
Known allergy
Pregnancy
CAD (vasoconstriction would exacerbate)
5
Q
Caution
A
Elderly, risk factors for CAD, lactation
Renal and hepatic dysfunction
6
Q
Drug-Drug interactions
A
Ergot containing drugs
MAOI’s
7
Q
Adverse Effects
A
Numbness, tingling, burning sensation feeling of coldness, weakness
Dysphasia Blood pressure alterations
