Ergot Derivates - Migraine Flashcards
1
Q
Drug Names
A
Dihydroergotamine
Ergotamine
2
Q
MOA
A
Block alpha adrenergic and serotonin receptors in brain to cause constriction of cranial vessels.
Reduce hyper perfusion of basilar artery vascular bed.
3
Q
Indication
A
Prevention or absorption of migraine or vascular headache
4
Q
Contraindications
A
Allergy
Impaired liver function
CAD, HTN, PVD (Due to vasoconstriction)
5
Q
Caution
A
Pruritis
Mal nutrition
6
Q
Drug-Drug interactions
A
Beta blockers
7
Q
Adverse Effects
A
Numbness, tingling of extremities, muscle pain.
Pulselessness, weakness, chest pain, arrhythmias
N/V/D
