Trintellix Module 3 Flashcards
Name the 9 possible symptoms of MDD
Depressed mood, lack of interest, suicidal ideation, significant appetite or weight changes., insomnia or hypersomnia, psychomotor retardation or agitation, fatigue of loss of energy, worthlessness or guilt, indecisiveness or diminished ability to think.
identify the tools that are use to assess cognitive functioning in patients with MDD.
Cognitive and physical functioning questionnaire ( CPFQ)
Digit symbol substitution test( DSST)
REy Auditory verbal learning test( RAVLT)
Describe the CPFQ test.
patient self administered with 7 questions. asseses patients cognitive and physical well being
uses a 6 point scale ranging from 1( greater than normal) to 6( totally absent)
Describe the DSST test.
patient self administered. a legend with 9 symbols corresponding to 9 digits and 3 rows of digits with a space below for patient to write the corresponding symbol.
assess attention, perceptual and motor speed, visual scanning ability and memory.
do as many as you can in 90-120 sec.
Describe the RAVLT test.
Physician administered comprising of 2 lists of 15 nouns.
assesses verbal memory and the nature and severity of memory dysfunction. tracks changes in memory over time.
patient recalls as many words as possible from from the first list. repeated 4 times.
Name the 8 psychosocial demographic factors involved in MDD.
psychosocial stressors Bereavement culture and ethnicity age sex pregnancy/postpartum depression family history comorbid associations
Describe the ASEX tool used to measure sexual dysfunction in patients with MDD.
Arizona Sexual Experiences Scale single assessment scale patient or physician administered. 5 questions 1 for each of the major global aspects of sexual dysfunction associated with MDD and the use of antidepressants. Sexual Drive Arousal Penile erection/vaginal lubrication ability to reach orgasm satisfaction from orgasm.
Describe the SDS.
Sheehan disability scale
Physician administered
asses functional impairment on 3 interrelated domains of work/school, social life, and family life.
5 questions: 3 rate the degree to which symptoms hav disrupted the patients life using a 10 point scale. 2 assess number of days in the last week the patient has missed school or work or hasn’t been about able to perform daily activities or felt unproductive.
Describe the CG1-1
Physician administered. to rate the change in a patients symptoms during treatment.
a single question the physicians answers based on any an all information at their disposal. as well as input form those in patients life.
What symptoms are assessed by the HAM-D
Depressed mood Guilt Suicidal thoughts presence of insomnia effect on work and intrests inability to speak presence of agitation anxiety somatic or genital symptoms hypochondria loss of insight loss of weight
How is the HAM-D scored?
each item is rated on a 0-2 or 0-4 scale the 3 point scale being applied to items for which quantification is difficult or impossible.
Describe the MADRS?
Physician administered to asses changes in depression symptoms over time. 10 questions measuring range of depression symptoms. Apparent and reported sadness inner tension reduced sleep reduced appetite difficulty concentrating weariness or exhaustion inability to feel pessimistic thoughts suicidal thoughts
How is the MADRS scored?
uses a scale of 0-6 to quantify symptom severity for each of the 10 items.
Name the 9 essential tools that were use in the vortioxetine clinical trials.
HAM-D MADRS ASEX MMSE SDS CGI-I CPFQ DSST RAVLT
