treponema pallidum

Question 1

gram stain + morphology

Answer 1

gram -
spirochete
teratogen

Question 2

causes

Answer 2

syphilis

Question 3

primary syphilis

Answer 3

chancre

Question 4

secondary syphilis

Answer 4

flu-like symptoms and non-itchy macular rash

Question 5

latent (hidden) syphilis

Answer 5

last 3-30 years
* can resolve, revert to secondary syphilis or progress to teriary syphilis

Question 6

tertiary syphilis

Answer 6

diffuse chronic inflammation and destruction of any organ

Question 7

3 major components of tertiary syphilis

Answer 7

granulomatous change (gummas)
cardiovascular syphilis
neurosyphilis

Question 8

congential syphilis

Answer 8

spontansous abortion, stillbirth, and neonatal death common

Question 9

2 serological tests

Answer 9

nontreponemal tests (measure Abs that develop against lipids released from damaged host cells)
treponemal tests (detect Abs against T. pallidum )