Treatments Flashcards

1
Q

Grave’s Disease- Best definitive tx?

A

Radioiodine Therapy

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2
Q

Cat Bite- Pasteurella tx?

A

Augmentin 5 days

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3
Q

Entamoeba Histolytica- liver abscess tx?

A

Metronidazole

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4
Q

Pediatric Viral Myocarditis tx

A

Diuretics + Inotropes

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5
Q

Nocardia tx

A

Bactrim 6-12 mos

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6
Q

Chagas Tx

A

Benznidazole

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7
Q

Bacillary Angiomatosis from Bartonella tx

A

Erythromycin

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8
Q

PCP PNA in HIV

A

Bactrim + Steroids (add steroids if PaO2 35

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9
Q

Prophy MAC in HIV (CD4

A

Azithromycin

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10
Q

Prophy PCP in HIV (CD4

A

Bactrim or Dapsone

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11
Q

Myasthenic Crisis tx

A

IVIG or Plasmapheresis, not both

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12
Q

Poor appetite in cancer tx?

A

Megesterol acetate

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13
Q

Pertussis tx

A

Azithromycin

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14
Q

Giant Cell Arteritis Tx

A

High-Dose Steroids

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15
Q

ADPCKD: Tx

New onset HTN with bilateral palpable masses

A

ACEi/ARBs

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16
Q

C. Dif Tx

A

PO metronidazole
PO vancomycin (for more severe or refractory)
WBC >15K , elevated creatinine
(Can use rectal vanc for Ileus)

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17
Q

Neuroleptic Malignant Syndrome

A
  1. ) Dantrolene
  2. ) Bromocriptine
  3. ) Amantadine
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18
Q

Parkinson’s

A

Mild: ACh antagonists: Benztropine, Trihexylphenidyl
DA releasers: Amantadine
Severe: Levodopa/carbidopa
COMT inhibitors, MAOi
DA agonistis: Pramipexole, Ropinirole

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19
Q

Restless Leg Syndrome

A

Pramipexole

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20
Q

Multiple Sclerosis

A

Glatiramir Acetate, Interferon B

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21
Q

Mild Hyponatremia
Moderate Hyponatremia
Severe Hyponatremia

A
  • Restrict fluids
  • Saline + Diuretic
  • 3% Saline (hypertonic) + conivaptan/tolvaptan (ADH receptor blockers): for symptomatic SIADH
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22
Q

Chronic SIADH

A

Demeclocycline

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23
Q

VSD tx

A

Conservative: Digoxin + Diuretics

Surgical : close the VSD

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24
Q

HACEK Endocarditis

A

Ceftriaxone

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25
Hib Epiglottitis
Ceftriaxone
26
Endometritis
Clindamycin/Gentamin
27
HIV : best initial regimen
1. emtricitabine 2. tenofovir 3. efavirenz
28
Infant of HIV + mother
Zidovudine for 6 weeks
29
Hereditary Angioedema
* Ecallantide or FFP : acutely * Androgens : danazol/ stanazol : chronic *ALWAYS PROTECT THE AIRWAY FIRST!
30
CVID
Treat infxns as they come | Chronic use of IVIG infusions
31
SCID
Bone marrow transplant is curative | *otherwise just treat infxns
32
What txs lower mortality in chronic angina?
BBs, Aspirin, Nitroglycerin (BAN)
33
What tx lowers mortality in HLD?
Statins
34
Unstable Ectopic Pregnancy
IVF, blood products, dopamine--> Surgery when stable
35
Septic Abortion
D&C + IV antibiotics (Levofloxacin + metronidazole)
36
Preterm Labor (without chorioamnionitis)
1. Betamethasone 2. Tocolytics (mag, terbutaline, ccb) 3. Amp + azithro as chorio prophy (swap amp for cefazolin or clinda if PCN allergic)
37
Gestational HTN
Methyldopa, Nifedipine, Labetalol,
38
Preeclampsia
Stabilize mom and deliver deliver deliver Prophy seizure: Mag sulfate HTN control: Hydralazine
39
Gestational DM
Insulin (NPH and aspart), Metformin and Glyburide | oral agents are NOT safe in pregnancy
40
Adenomyosis (globular, boggy uterus)
Hysterectomy
41
Endometriosis
NSAIDS, OCPs : mild Danazole, Leuprolide : moderate (suppress LH/FSH) Surgery: severe Done childbearing? TAH-BSO
42
Uveitis
topical steroids
43
Acute angle closure glaucoma
Acetazolamide Pilocarpine Mannitol Trabeculoplasty
44
Open Angle Glaucoma
**Prostaglandin Analogues- prosts **Topical BB Topical carbonic anhydrase inhibitors -amides pilocarpine Trabeculoplasty
45
CRVO
Ranibizumab (Lucentis- also used for wet mac degen)
46
CRAO
100% Oxygen, Ocular massage | Acetazolamide, ant. chamber paracentesis
47
Panic Disorder
Acute Management: Benzodiaz. | Chronic Tx: SSRIs
48
Adjustment disorder
Psychotherapy, Not meds.
49
ADHD
First Line: methylphenidate (Concerta) or dextroamphetamine Second Line: atomoxetine- Strattera (NE reuptake inhib) *Strattera has better side-effect profile
50
Bipolar Depression
Lithium or Lamotrigine
51
Cyclothymia
Carbemazepine, Lithium, Valproate, psychotherapy
52
Atypical Depression (Wt gain, inc appetite, more sleep, worse mood in the evenings)
SSRIs or MAOis (SSRIs are safer)
53
Seasonal Affective Disorder
Phototherapy + Buproprion
54
Postpartum Psychosis
Antipsychotic, lithium, antidepressants
55
Acute Dystonic Reaction (hrs to days of antipsych) | -includes oculogyric crisis/torticollis
Benztropine or Diphenhydramine
56
OCD
SSRI's : First Line (including fluvoxamine) Clomipramine : Second Line Behavioral Therapy: exposure and response prevention
57
PTSD
Paroxetine Sertraline Prazosin for nightmares
58
GAD
SSRIs, buspirone, and venlafaxine
59
Alcohol withdrawal Benzos
Chlordiazepoxide, Lorazepam, Oxazepam
60
Anabolic Steroid Withdrawal
SSRIs (presents with HA/depression/anxiety)
61
Opiate WIthdrawal
Clonidine Methadone Buprenorphine (partial mu agonist)
62
Narcolepsy
Modafinil Forced naps Methylphenidate/dextroamphetamine
63
Insomnia
Good Sleep Hygiene | Zolpidem, Eszopiclone, Zaleplon
64
Tinea Versicolor
Selenium Sulfide Shampoo
65
Methemoglobinemia
100% oxygen and methylene blue*
66
Tropical Sprue
Folate + Doxycycline
67
Organophosphate Toxicity
Pralidoxime (acetylcholine esterase activator) | Atropine (works quicker)
68
Brown Recluse Spider Bite
Debride necrosis Steroids Dapsone
69
Black Widow Spider Bite
Calcium (for repletion) | Antivenin
70
Head Trauma, to lower ICP
HOB elevated Intubate-->Hyperventilate Mannitol Drain blood/fluid
71
Wolff-Parkinson-White Syndrome (delta wave +short PR) *DEFINITIVE DX WITH EP STUDIES*
Acute: Procainamide, amiodarone Chronic: Ablation (curative) of abnormal conduction tract around AV node *Don't use blockers of AV node (dig/ccbs), as these will force conduction through the abnormal WPW pathway
72
Third Degree AV block or Second Degree type II AV block (EVEN if asymptomatic)
Pacemaker
73
SVT
Vagal Maneuvers | Adenosine
74
Symptomatic sinus bradycardia
Atropine
75
Penile Fracture
Retrograde Urethrogram followed by surgery
76
Scaphoid Fracture (even with negative initial xray)
Wrist immobilization
77
Intrahepatic Cholestasis of Pregnancy
Ursodeoxycholic Acid
78
N. Meningitis
Ceftriaxone AND rifampin/cipro/ceftriazone to close contacts
79
H. Ducreyi (Chancroid)
Azithromycin (1 dose)
80
Lymphogranuloma venereum (tender/suppurative inguinal LAD)
Doxycycline
81
Syphillis
Primary/secondary: IM Penicillin or Doxy if allergic | Tertiary: IV penicillin or desensitize if allergic for tertiary
82
Scabies
Permethrin cream for everyone, all over | Really bad- crusted? Ivermectin
83
Pediculosis (crabs)
Permethrin
84
Pyelonephritis
Outpatient: Cipro Inpatient: Ceftriaxone, or amp/gent until cultures are back
85
Chronic prostatitis
Bactrim for 6-8 weeks
86
Achalasia
Pneumatic Dilation | Botulinum toxin injection
87
Nutracker esophagus/ Esophageal Spasm
CCB
88
Unstable Angina
BB, heparin, GIIbIIIa receptor BLOCKER CLOPIDOGREL ACEinhibitor/ARB
89
Prinzmetal angina (coronary spasm)
Nitro- acutely | CCB- chronically
90
DVT
IV/subQ hep bridged to warfarin for 3-6 mos | INR: 2-3
91
Primary pulmonary hypertension
``` Prostacyclin Antiendothelin (bosentan) PDE-5 inhibitors CCB Heart/lung transplant ```
92
HOCM
BB and disopyramide
93
WPW syndrome
Pocainamide/quinidine
94
Vfib
Defib, epi, vasopressin, amio/lidocaine
95
Wilson's Disease
Pennicillamine (Cu chelator) | Oral zinc is recommended- prevents Cu absorption
96
Uncomplicated Cystitis
Trimeth-Sulf (3-days) Nitrofurantoin (5-days) Fosfomycin (one dose) ... if resistant .. Fluoroquinoloes
97
Hx of Rheumatic Fever: prophy
RF w.o carditis: PCN for 5 years or until 21 RF w. carditis but no residual valve problem: PCN for 10 years or until 21 RF with carditis + valve problems: PCN for 10 years or until 40
98
Uric Acid Kidney Stones
Alkalinize urine with potassium citrate | Limit dietary purines
99
Neutropenic Fever (ANC
Broad spectrum pseudomonal monotherapy 1. ) Zosyn 2. ) Meropenem 3. ) Cefepime
100
Asymptomatic Bacteruria in pregnancy
Nitrofurantion x7 days
101
Meniere's Disease
Short term tx: Antihistamines, Anticholinergics, Benzos | Long-term: diuretics
102
Uterine Atony
Uterine Massage Fluid resuscitation Oxytocin, methylergonovine, carboprost
103
Esophageal Varices Ppx
Propranalol, nadolol (Nonselective BB)
104
Hoarding Disorder
SSRIs, CBT
105
Ascites
Fluid restriction Spironolactone Loops Frequent taps
106
Low EF/systolic dysfxn OR valvular incompetence
ACEi/ARBs
107
ST-segment depression ACS
Give heparin right away!
108
Everyone with systolic dysfunction (low EF) needs..
ACEi, BB, spironolactone, diuretics, digoxin | Approved BB: metoprolol, bisoprolol, carvedilol Spironolactone for CHF stage III, IV
109
Mortality benefit in systolic dysfunction...
BASH'D | BB, ACEi, Spironolactone, Hydralazine, Defibrillator
110
Chemical Eye Burns
``` Copious Irrigation (Alkali worse than Acid- don't play chemist) ```
111
Chalazion (painless)
Warm compresses first.. | Inject steroids
112
Herpes simplex keratitis
``` Topical antiviral (idoxiuridine, trifluridine) NO STEROIDS ```
113
Kleptomania
Psychotherapy
114
Flail Chest
Intercostal nerve block
115
Hepatic Encephalopathy
Fluids, electrolyte replacement (POTASSIUM) Lactulose Rifaximin
116
Disk herniation (+SLR) WITHOUT FND
Return to normal activities NSAIDs and muscle relaxants If 4-6weeks no improvement- MRI/CT
117
Toxic Megacolon
``` Bowel rest (NPO), NG-tube, IV steroids If no improvement- emergency sx (subtotal colectomy + end-ileostomy) ```
118
VIPoma
Octreotide
119
PNH (CD55, CD59 defic)
Predisone, Eculizumab (blocks C5 in complement pathway)
120
Guillain Barre Syndrome
IVIG/Plasmapheresis
121
Fibromuscular Dysplasia
Angioplasty + stenting (definitive) | Med manage HTN
122
Emphysematous cholecystitis
IV fluids, electrolytes Cholecystectomy IV abx for gram - and anaerobes (unasyn, zosyn, etc)
123
Carcinoid Tumor
Surgery, radiation, chemotherapy, hormonal supp (Octreotide)
124
Legionella/Legionaire's Disease
Floroquinolones or newer macrolides
125
UTI in Pregnancy
Amoxicillin
126
Lyme Disease
Early: amoxicillin or Doxy Late: ceftriaxone (carditis or CNS)
127
Community acquired PNA
Fluoroquinolones = best therapy
128
Diverticulitis
FQs + metronidazole (except moxiflox can be used alone)
129
H. Ducreyi
Single dose of azithromycin
130
Torsades dePointes
Magnesium sulfate | *if 2/2 quinidine use- Na Bicarb
131
Empiric pyelonephritis tx (cx pending)
Amp-Gent
132
Staph IE in prosthetic valves
Nafcillin or Vanco + Rifampin
133
Bronchitis
Supportive tx, abx don't typically help
134
Neonatal meningitis
Amp-Gent
135
Child/adult meningitis
3rd gen ceph/vanc
136
Chlamydia pneumonia
8 yo: doxycyclin/azithromycin
137
CMV PNA
Valganciclovir
138
Sporothrix (thorn bush)
Itraconazole
139
Aspergillosis
Voriconazole
140
Neurocysticercosis
Albendazole, praziquantel
141
Diptheria
Antitoxin plus penicillin OR erythromycin
142
Impetigo
Non-bullous - Mupirocen | Bullous- Dicloxacillin
143
Kid
INH for 3 mos and re-test PPD
144
CAD in a severe asthmatics
CCB : verapamil/diltiazem
145
Prinzmetal angina
CCB
146
HTN crisis from MAO
IV Phentolamine
147
Bipolar in pregnancy
Benzos
148
Panic disorder with agoraphobia
(Check EKG first, cardiac enzymes, echo, T4, etc) Benzo- short term SSRI- chronic (4-6 weeks for efficacy)
149
Insomnia
Sleep hygiene, Zolpidem, eszopiclone, zaleplon
150
Paranoid Personality Disorder
Low dose antipsychotic
151
Alzheimers
Rivastigmine, Donepozil, Memantine
152
AIHI - warm agglutinin
High dose glucocorticoids Rituximab Splenectomy
153
Epidural Hematoma
Craniotomy
154
Chronic Subdural Hematoma
Craniotomy (can reverse dementia)
155
Myocardial Contusion
MONA- BASH (just like MI)
156
Pelvic trauma
Give Blood and track H&H, it will tamponade off
157
Fecal incontinent (>3 yo, more than 1 month)
Fiber, biofeedback, dextranomer/hyaluronic acid, CR surgery
158
ABPA
Oral steroids (inhaled NOT effective), Itraconazole if recurrent
159
Ventilator-Associated PNA
Two pseudomonal coverage | One MRSA coverage
160
HIV positive with PCP PNA + G6PD deficiency
Pentamidine
161
SBP
3rd gen cephalosporin | If 2+ organisms or PMNS >250 - add metronidazole
162
Hyperkalemia
``` Stabilize membranes -ca gluconate IV insulin/glucose - quickest Albuterol Kayexalate Diuretics (furosemide, tzd) ```
163
Hemodynamically unstable with PE
Thrombolytics
164
Stable PE -obvious
Heparin- bridge to warfarin
165
Dupuytrens contracture
TLC! Triamcinolone Lidocaine Collagenase injections
166
First like rheumatoid arthritis and psoriatic arthritis
MTX (take folate!)
167
Pityriasis Rosea
Steroids or UV light
168
Seborrheic dermatitis
Topical antifungals and steroids because this is a HYPERsensitivity to dermal infxn -like ABPA is a HYPERsensitivity to fungal lung infxn (treated with oral steroids + itraconazole if nec)
169
Pemphigus vulgaris
Systemic steroids Azathioprine or mycophenolate to get off steroids Rituximab
170
Nonallergic Rhinitis (onset of stuffiness >20yo without sneezing/eye symptoms)
Intranasal antihistamines + Intranasal anticholinergics
171
Bipolar manic episode (Chronic)
Lithium at LEAST one year after one episode
172
Toxoplasmosis
Pyramethamine, Sulfadiazine