Treatment Resistant Schizophrenia Flashcards

1
Q

ESSENCE

A

Failure to respond to two or more antipsychotic medications given in therapeutic doses for >=6 weeks

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2
Q

AETIOLOGY

A
  • Neurodevelopment factors
  • Drug non-compliance
  • Lack of adequate treatment
  • Aggravating factors despite treatment
    • Alcohol or drug misuse
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3
Q

MANAGEMENT

A
  • Clarify diagnosis
  • Address comorbidity
  • Pharmacological intervention - clozapine
  • Rehabillitation
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