Treatment of Pulmonary HTN Flashcards

1
Q

What are 3 drugs we can use to treat pulmonary HTN?

A
  1. Bosentan
  2. Prostacyclin
  3. Sildenafil
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2
Q

What is the mechanism of Bosentan?

A

Endothelin receptor antagonist

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3
Q

How is Bosentan administered?

A

Orally

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4
Q

What is the analog of prostacyclin given as a drug for pulmonary HTN?

A

Epoprostenol

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5
Q

How is epoprostenol administered?

A

Slow IV infusion through a pump

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6
Q

Why is sildenafil used to treat pulmonary HTN?

A

Inhibits type V PDE which is not only found in the corpus cavernosum but is also found in the lung vasculature

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