Treatment of Pulmonary HTN Flashcards
1
Q
What are 3 drugs we can use to treat pulmonary HTN?
A
- Bosentan
- Prostacyclin
- Sildenafil
2
Q
What is the mechanism of Bosentan?
A
Endothelin receptor antagonist
3
Q
How is Bosentan administered?
A
Orally
4
Q
What is the analog of prostacyclin given as a drug for pulmonary HTN?
A
Epoprostenol
5
Q
How is epoprostenol administered?
A
Slow IV infusion through a pump
6
Q
Why is sildenafil used to treat pulmonary HTN?
A
Inhibits type V PDE which is not only found in the corpus cavernosum but is also found in the lung vasculature