Treatment of HF

Question 1

What drugs should be used in advanced heart failure?

Answer 1

Aldosterone antagonists
1- spironolactone
2- eprelenone

Question 2

Which drug causes gynecomastia and menstrual irregularities?

Answer 2

Spironolactone

Question 3

Spironolactone may cause hyperkalaemia with which group of drugs?

Answer 3

ACE inhibitors

Question 4

Which drug decreases excretion of digoxin?

Answer 4

Spironolactone

Question 5

Which group of drugs blocks Na-Cl transporter in proximal tubule?

Answer 5

Thiazide and thiazide-like

Question 6

which group of drugs inhibit Na-K-Cl in ascending loop on henle?

Answer 6

Loop diuretics

Question 7

Which drugs improve mortality in HF?

Answer 7

Nitrates + Hydralazine
ACE inhibitors
Spironolactone
Beta-Blockers

Question 8

When should nitrates + hydralazine be used? and what is the most common adverse effect?

Answer 8

1- if a patient can’t tolerate BBs and ACEI

2- if additional vasodilators are needed

Question 9

Which drug cause Lupus-like syndrome?

Answer 9

Hydralazine

Question 10

Hydralazine may cause hypotension with which drug?

Answer 10

Antihypertensives

Question 11

Which drugs have the most promising results in reducing ventricular dysfunction?

Answer 11

1- Bisoprolol
2- Carvedilol
3- Extended-release metoprolol

Question 12

What group of drugs is used for acute HF in hospital?

Answer 12

B-adrenergic agonist

Sodium Nitroprusside

Question 13

which drug increases risk of mortality in long term use?

Answer 13

Milorone

Question 14

which drug is contraindicated in IHD?

Answer 14

Milorone

Question 15

Which drug is indicated in HF with atrial fibrillation?

Answer 15

Digoxin

Question 16

What are the first-line drugs used for HF?

Answer 16

ACEI and BBs

Question 17

Second-line drugs?

Answer 17

Aldosterone antagonists
ARBS
Hydralazine + nitrates

Question 18

If first & second line drugs fail, what is your next step?

Answer 18

Cardiac resynchronization therapy

Digoxin