TREATING BACTERIAL INFECTIONS

Question 1

Community acquired atypical pneumonia (Mycoplasma and Legionella)

Answer 1

1. Azithromycin
2. Doxycycline (not for legionella)
3. Moxifloxacin - quinolones

Question 1

Lyme disease

Answer 1

1. Doxycycline
2. Amoxicillin
3. Ceftriaxone
4. Penicillin G

Question 2

UTI (bladder, empiric)

Answer 2

1. Trimethoprim + sulfamethaxazole
2. Nitrofurantoin
3. Fosfomycin
4. Norfloxacin - lots of resistance
5. Ciprofloxacin - lots of resistance

Question 2

What does metronidazole treat?

Answer 2

• C. diff enterocolitis - mild
• # 1 for Strict anaerobes (+/-)
• # 2 for gastric ulcers (H. pylori) with omeprazole

Question 3

Gonorrhea

Answer 3

1. Ceftriaxone + azithromycin or doxycycline

Question 3

C. diff enterocolitis

Answer 3

1. Metronidazole - mild
2. Vancomycin (oral) - moderate to severe
3. Fidaxomicin - 3rd line

Question 4

Bacterial Meningitis (empiric)

Answer 4

Ceftriaxone + vancomycin

Question 5

Strict anaerobes (+/-)

Answer 5

1. Metronidazole
2. Tigecycline - IV
3. Cefoxitin
4. Amoxicillin + clav
5. Ticarcillin + clav
6. Clindamycin
7. Imipenem + cilastatin
8. Chloramphenicol

Question 7

Surgical Prophylaxis

Answer 7

1. Cefazolin

Question 10

Gram positive STREP THROAT

Answer 10

1. Penicillin V
2. Penicillin G procaine or benzathine
3. Cephalexin (1st gen but all gens work)
4. Erythromycin - for pen allergies!
5. Clindamycin - for pen allergies!

Question 11

What does vancomycin treat?

Answer 11

• # 1 for gram positive STAPH (MRSA)
• *C. diff *enterocolitis (oral - moderate to severe)
• # 1 for bacterial meningitis (empiric) with ceftriaxone!
• # 1 for strict anaerobes (+ only)

Question 12

Gastric Ulcers (H. pylori)

Answer 12

1. Clarithromycin
2. Metronidazole + omeprazole
3. Amoxicillin + ranitidine
4. Tetracycline
5. Use 2 drugs

Question 13

Gram positive STAPH (MSSA)

Answer 13

1. Oxacillin
2. Amoxicillin + clavulanate
3. Linezolid
4. Cefazolin (IV), Cephalexin (Oral)
5. Erythromycin
6. Daptomycin

Question 14

Middle ear infections (empiric)

Answer 14

1. Amoxicillin - high dose
2. Azithromycin - for bplactam alelrgic pts
3. TMP-SMX

Question 15

Gram NEGATIVES + pseudomonas

Answer 15

1. Tigecycline - not pseudomonas
2. Piperacillin + tazobactam
3. Ceftriaxone
4. Cefepime
5. Aztreonam
6. Imipenem - also for ESBL’s
7. Tobramycin, amikacin
8. Polymyxin B (topical)

Question 16

Strict anaerobes (+ only)

Answer 16

1. Vancomycin
2. Pen G
3. Daptomycin

Question 17

Gram positive STAPH (MRSA)

Answer 17

1. Vancomycin
2. Linezoild (IV or oral)
3. Daptomycin
4. Tigecyclin

Question 18

Syphilis

Answer 18

1. Penicillin G - benzathine
2. Minocycline or doxycycline - for pen allergies!

Question 19

Chlamydia

Answer 19

1. Azithromycin
2. Doxycycline
3. Ciprofloxacin
4. Norfloxacin

Question 20

What does azithromycin treat?

Answer 20

• # 1 for chlamydia
• # 1 for gonorrhea with ceftriaxone
• # 1 for community acquired atypical pneumonia (Mycoplasma and Legionella)
• # 2 for middle ear infections (for b-lactam allergic pts!)