transporting across membranes Flashcards

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1
Q

what attracts other polar molecules

A

polar phosphate head

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2
Q

how does a bilayer form

A

-hydrophobic fatty acid tails are oriented inwards towards the middle and point away from water and the
- hydrophobic heads are oriented towards the outside and point towards the water
- the hydrophilic heads make contact with watery cytoplasm and extracellular fluid

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3
Q

what is the word to describe the cell surface membrane

A

selectively permeable

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4
Q

what does the cell membrane consist of

A

proteins (channel / carrier / receptor )
glycoproteins
phospholipids
cholesterol
carbohydrates

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5
Q

why is the cell membrane called the fluid - mosaic model

A

because phospholipids form a bilayer that are constantly moving around relative to one another giving the membrane a FLUID structure

different protein molecules are unevenly distributed throughout the membrane forming a MOSAIC

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6
Q

what is the selective permeability of the cell membrane related to

A

type and distribution of specific proteins and phospholipid molecules present in the membrane

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7
Q

what is the function of phospholipids in the cell membrane

A

form a bilayer (hydrophilic heads outwards in watery extracellular fluid or cytoplasm, hydrophobic tails inwards attracted to each other)

most abundant molecule in cell membrane

allows lipid-soluble (non polar) molecules ONLY to pass through simple diffusion

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8
Q

what is the function of cholesterol in the cell membrane

A

decreases permeability and increases the stability of membrane

more cholesterol = less fluidity of membrane

different types of cells have different proportions of cholesterol

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9
Q

what is the function of channel proteins

A
  • are like pores that only allow specific charges ions or small molecules to pass through facilitated diffusion, they can be opened or closed and let ions pass right through
  • proteins have a specific tertiary structure so they are specific and can only transport molecules that are complementary to the shape of channel protein
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10
Q

how do Na+ ions pass through membrane

A

ONLY through sodium ion channel proteins

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11
Q

what is the function of carrier proteins in the cell membrane

A
  • aid the transport of ions / polar molecules and large molecules by facilitated diffusion and active transport
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12
Q

what is the function of receptor proteins in the cell membrane

A
  • act as specific receptors for complimentary molecules
  • only specific molecules can bind to specific receptor proteins
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13
Q

what is the function of glycoproteins in the cell membrane

A
  • composed of carbohydrates and proteins and are important for cell to cell recognition (often acting as antigens)
  • glycoproteins are produced in the golgi body
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14
Q

what are aquaporins

A

special type of channel proteins specific to water ,cell that has lots of aquaporins is very permeable to water and carries osmosis easily

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15
Q

what is simple diffusion

A

net movement of molecules from an area of higher concentration to lower concentration across a partially permeable membrane

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16
Q

when does NET diffusion stop

A

when the molecules have reached equilibrium

17
Q

what molecules are transported using simple diffusion

A

non -polar , small , lipid-soluble molecules

18
Q

what is ficks law

A

rate of diffusion is proportional to = (surface area * conc gradient ) / diffusion distance

19
Q

what factors affect rate of diffusion

A

temperature- increased KE so faster rate of diffusion

surface area - larger SA more space for molecules to pass through

concentration gradient- as concentration difference increases, rate of diffusion increases

  • diffusion distance
20
Q

what is facilitated diffusion

A

when specific proteins (carrier or channel) help specific molecules to pass through the phospholipid bilayer

21
Q

why can hydrophilic ( water soluble, charged or large ) substances not pass between hydrophobic tails

A

because the fatty acid tails are non- polar and they repel polar molecules

22
Q

how do specific molecules pass through membrane using proteins

A

channel and carrier proteins are a specific shape because of their unique tertiary structure so they only transport specific molecules that are complementary to the binding site

23
Q

what does it mean when in a graph for rate of facilitated diffusion, the graph levels

A

because all carrier proteins are saturated/binding site is full

number of carrier proteins can become a limiting factor

24
Q

what is osmosis

A

net movement of water particles from a higher water potential to a lower water potential through a selectively permeable membrane

25
Q

what is water potential ( kPa )

A

pressure exerted by free water molecules whilst moving and colliding

more free moving water = more pressure = higher water potential

26
Q

what does adding a solute do to the water potential

A

lowers it , makes solution negative

27
Q

what is an isotonic solution

A

2 solutions with same water potential

28
Q

what is an hypotonic and hypertonic solution

A

hypotonic - has lower water potential

hypertonic solution - has higher water potential

29
Q

what is active transport used for

A

transport molecules across the membrane against their concentration gradient, from lower concentration to higher concentration

30
Q

why does active transport only use carrier proteins

A

because it requires a specifically shaped carrier protein with a complementary binding site, that only complementary molecules bind to

31
Q

where is the energy for active transport come from and what is it used for

A

hydrolysis of atp which is produced during respiration

and is used to change shape of carrier protein (by phosphorylation)

the change in protein shape transports the molecule across the membrane into an area where the concentration of the molecule is relatively high

32
Q

give types of bulk transport

A

exocytosis and endocytosis

33
Q

give one use of exocytosis

A

move enzymes and glycoproteins from the golgi apparatus to the cell membrane to secrete proteins

34
Q

what is needed for exocytosis

A

atp required to move vesicles to cell surface membrane and the vesicles fuse with the membrane

atp also needed for endocytosis

35
Q

what molecules are transported by active transport

A

ions and glucose

36
Q

what happens if aerobic respiration is inhibited

A

Active transport can’t occur as there is no/less ATP. All the other types of transport can still continue until equilibrium is reached.

37
Q

What happens if the tertiary structure of the carrier protein changes?

A

Facilitated diffusion/active transport can’t occur (because the binding site has changed shape and is no longer complementary to the molecule, therefore they will not fit/bind).