Transport of O2 Flashcards
Adaptations of Erythocytes (RBCs)
Biconcave shape => maximises surface area for gas exchange
Small +flexible to pass through through narrow capillaries
No nucleus => move room to carry respiratory gases
Packed with haemoglobin (HB)
Haemoglobin
Protein making up 95% of mass of RBC + is means of transport of oxygen around the body
Made of 4 polypeptide chains each bonded to 1 haem group
Each haem group contain 1 O molecule so ecah HB carries 4 Os max
Oxygen in the lungs diffuse into RBCs
O2 diffuses into blood plasma - down conc gradient to RBC - and binds to HB
Oxygen in respiring tissues
Oxygen dissociates from oxyhaemoglobin and diffuses out of erythocytes to respiring cells
Effect of O2 conc on diffusion
O binds to HB when O is at high conc + dissociates from HB at low conc
=> conc of gas in a mixture of gases can be qualified as partial pressure
When oxygen dissociation curve shifts to left (e.g. fetal HB)
The <= the curve, the more readily the pigment associates with O2 but the less readily it dissociates
When oxygen dissociation curves shifts to the right
The more => the curve the less readily the pigment asociates w/ O2 but the less readily it dissociates