Transport of Gases

Question 1

Partial pressure of oxygen in alveoli artery and veins?

Answer 1

Alveoli: 100
Artery: 95
Vein: 40

Question 2

Partial pressure of carbon dioxide in alveoli artery and veins?

Answer 2

Alveoli: 40
Artery: 40
Vein: 46

Question 3

What occurs to partial pressure of O2 in the lungs in hyper and hypoventilation respectively?

Answer 3

Hyperventilation: increase
Hypoventilation: decrease

Question 4

How many layers do gases have to diffuse to in order to reach the Hb?

Answer 4

12 layers affecting diffusion constants

Question 5

What is important to note about the Fick law?

Answer 5

Each can be affected by a diseased condition

Question 6

Difference in diffusion limited and perfusion limited?

Answer 6

Diffusion limited: abnormal condition in which the gases have to diffuse through a thicker wall (fibrosis; can’t diffuse)
Perfusion limited: dependent on blood flow (more oxygen in capillary only if increased blood flow; gas reaches saturation point in the blood)

Question 7

How can exercise be diffusion limited?

Answer 7

There is more blood flowing than oxygen being ventilated to saturate the blood

Question 8

Formula pulse oximeter uses?

Answer 8

SaO2= (HbO2 content/HbO2 capacity)x100%

Question 9

What do pulse oximeters tell you?

Answer 9

Just concentration of O2 in blood nothing else do not extrapolate knowledge (just don’t)

Question 10

What is the concentration of 2,3-BPG in pregnant women versus normal?

Answer 10

Higher 2,3-BPG

Question 11

What Hb can give you an idea of diabetic management indicator?

Answer 11

HbA1c when it is highly glycosylated

Question 12

What amount of CO2 is dropped off from systemic to lungs?

Answer 12

Systemic 52 mL/dL- pulmonary 48 mL/dL= 4 mL/dL

Question 13

What is the major way that CO2 is transported in blood?

Answer 13

HCO3-

Question 14

What is the Haldane effect?

Answer 14

Higher oxygen content decreases the affinity of CO2 for Hb