Transport Across Membranes Flashcards

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1
Q

What is a cell membrane made out of?

A

Phospholipids bilayer

The hydrophilic heads and hydrophobic tails separate the two environments from the external and internal sides of a cell.

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2
Q

What are the main components in a cell membrane? And give their functions

A

Phospholipid bilayer- separates internal and external environments

Protein channels- transports charged ions across the membrane

Protein carriers- transports small molecules across the membrane

Cholesterol- regulates fluidity of the membrane

Cytoskeleton filaments- provides mechanical strength to the membrane

Glycolipids- antigens for self recognition

Glycoproteins- antigens for self recognition

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3
Q

What are the main functions of the plasma membranes?

A

Partially permeable barriers:
Allows small molecules to diffuse through and lipid soluble molecules to diffuse through. Contains channel and carrier proteins for the non polar or charged molecules which may be too big to move through

Regulation of substances in and out of the cells

Regulation of metabolic pathways

Antigens - self recognition

Cell signalling

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4
Q

What is the purpose of a membrane within cells?

Not cell surface/plasma membrane

A

Separate organelle contents from the cytoplasm of a cell

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5
Q

Why is the cell membrane described as fluid mosaic?

A

Cell membranes are aqueous and have cholesterol to regulate the fluidity of the membrane (hence fluid part)

Then phospholipids are all aligned adjacent to one another creating a mosaic pattern

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6
Q

What happens to phospholipids when the temperature decreases?

A

Saturated fatty acids become compressed so the fluidity decreases however cholesterol and the unsaturated fatty acids make the membrane more fluid to maintain their normal fluidity.

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7
Q

What happens to phospholipids when the temperature increases

A

More kinetic energy and therefore the membrane becomes more fluid
But
Cholesterol resists these changes and maintains the normal fluidity levels

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8
Q

What happens to the proteins in a cell membrane when the temperature is increased?

A

The tertiary structure of the proteins change and the proteins denature

Cytoskeleton threads are proteins that hold the membrane in place and therefore if they denature, the cells membrane deforms causing the cell to die.

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9
Q

What kind of solvents would destroy cell membranes?

A

Acetone and ethanol

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10
Q

What is a passive process?

A

A process which does not require metabolic energy from ATP

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11
Q

What is diffusion?

A

The passive movement of molecules from an area of higher concentration to and area of lower concentration.

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12
Q

What is facilitated diffusion?

A

Diffusion of molecules across a partially permeable membrane through carrier or channel proteins from an area of higher concentration to an area of lower concentration

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13
Q

What is osmosis?

A

Movement of water molecules from an area of higher water potential to an area of lower water potential across a partially permeable membrane

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14
Q

Define turgid?

A

A plant cell fully filled with water

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15
Q

Define plasmolysed?

A

Plant cell whose cell membrane has pulled away from the cell wall due to a loss of water

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16
Q

Define flaccid

A

A plant cell that is limp due to a reduction of pressure against the cell wall

17
Q

Define crenation

A

Lysis of an animal cell due to influx of water

18
Q

What factors affect the rate of diffusion?

A
Temperature
Diffusion distance
Size of diffusion molecule
Surface area
Concentration gradient
19
Q

What is water potential?

A

A measure of the tendency of water molecules to diffuse from one region to another

20
Q

What is active transport?

A

Movement of molecules against the concentration gradient from an area of lower concentration to an area of higher concentration which requires energy from ATP

Also requires channel/ carrier proteins

21
Q

How does ATP help in the transport of molecules across a membrane?

A

The hydrolysis of ATP releases energy to slightly change the shape of carrier proteins enabling a specific molecule to bind to it and be taken into a cell.

22
Q

What is endocytosis?

A

Movement of molecules in to a cell

23
Q

What is exocytosis?

A

Movement of molecules out of a cell

24
Q

What is pinocytosis?

A

Where a Pinocyte engulfs a particle that is a liquid

25
Q

What is phagocytosis?

A

When a phagocyte engulfs a small cell or particle such as bacteria