Transport across cell membranes Flashcards
What is a plasma membrane?
All membranes in and around cells and membrane bound organelles.
What is the structure and function of the plasma membrane?
Phospholipid bi layer, cholesterol, proteins, glycolipids, glycoproteins.
Separates cell contents from external environment. Controls what enters and exits the cell. Identifies cell as self. Site of chemical reactions.
What is the cell surface membrane?
Specifically a plasma membrane that surrounds cells and forms the boundary between the cytoplasm and the environment.
What is the role of the phospholipid bilayer in the plasma membrane?
Lipid soluble material is able to move into and out of the cell.
Water soluble material is unable to move in or out of the cell.
The membrane is flexible and self-healing.
How are proteins embedded in the plasma membrane?
Occur on the surface only or completely span the bilayer from one side to the other
What is the role of proteins which are embedded on the surface of a plasma membrane?
Mechanical support, or as cell receptors
What is the role of proteins which span the width of the plasma membrane?
Protein channels- water filled tubes allowing water soluble ions to diffuse across.
Carrier proteins- Bind to molecules and change shape to move them across
What are the overall roles of proteins in the membrane?
1 Structural support
2 Channels for water soluble substances
3 Allow active transport
4 Cell surface receptors for identifying cells
5 Cell adhesion
How does cholesterol interact with water
Hydrophobic
What does cholesterol do to other molecules in the membrane?
Hold phospholipids tightly. Prevent water loss
What is the role of cholesterol in the membrane?
Reduce lateral movement of other molecules.
Make the membrane less fluid at high temperatures.
Prevent leakage of water
How can the movement of particles be described?
Random
Constant due to kinetic energy
Constantly bouncing of each other
Definition of diffusion
Net movement of molecules/ ions from a region where they are highly concentrated to one where their concentration is lower until evenly distributed
What kind of molecules can diffuse through the cell surface membrane?
Small, non-polar molecules e.g. oxygen and CO2
What does polar mean?
Molecule has a positive charge on one side and a negative charge on the other