Transport Flashcards
3 ways to cross the plasma membrane
Simple diffusion
Passive transport
Active transport
Simple diffusion
Small, uncharged molecules or small, polar molecules (less than 90 daltons; water, ethanol, glycerol, etc.)
Facilitated diffusion or passive transportation
High conc. to low conc.
Transport mediated or channel mediated
Transport proteins follow Michaelis-Menten equation
Highly specific
Electrochemical gradient can contribute to passage of charged solutes
3 types of carrier proteins
Uniport
Symport
Antiport
Uniport
Transports one molecule
Symport
Transports 2 molecules in the same direction
Antiport
Transport 2 molecules in opposite directions
Channel proteins
Hydrophilic channels through membrane
Porins (bacteria and mitochondria; large and non-specific)
Aquaporins (rapid influx of water)
Ion channels
Specific for specific ions (K, Na, Ca)
Most are gated
Conformation change allows control of passive ion movement
Stress gated channel
Venus fly trap: trigger on leaf opens channel that changes turgor pressure- leaf snaps shut
Human ear: sound vibrations tilt hair cells, causing linking filament to pull channel open
3 mechanisms for gating ion channels
Voltage gated (changing charge changes conformation) Ligand gated (binding of molecule changes conformation) Stress gated (mechanosensitive; pressure opens gate)
Energy sources for active transport
Coupled transporter
ATP-driven pump
Light-driven pump (bacteriorhodopsin)
Coupled transporter
1 molecule goes with gradient; 1 molecule goes against gradient
Antiport
ATP-driven pump
Half of cell’s ATP is used for transport
Sodium potassium pump
ATP-driven pump: phosphorylation of the pump causes conformational change
Antiport: transports Na with gradient into cell and K against gradient out of cell
P-type transporter