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Cell Bio > Cell Junctions > Flashcards

Cell Junctions Flashcards

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Biology 101 flashcards
1
Q

4 types of tissue

A

Epithelial
Connective
Muscular
Nervous

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2
Q

Fibroblasts

A

Produce connective tissue

Secretes collagen

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3
Q

Bone

A

Collagen and mineralization

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4
Q

Collagen

A

20% of body’s protein mass

Fibers are placed at 90 degree angles to each other- strength (like plywood)

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5
Q

Procollagen

A

Fibroblasts secrete this

Proteases break it down into collagen

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6
Q

Integrins

A

Link collagen to cells
Used in binding and signaling
Membrane-spanning protein

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7
Q

Fibronectin

A

Link collagen to cells

Secreted protein

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8
Q

Proteoglycan

A

Protein that has glycosaminoglycan (GAG) associated with it

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9
Q

Glycosaminoglycan (GAG)

A 
Present in connective tissue
Attracts water (polar)- cushioning
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10
Q

GAGs in cartilage

A 
Chondroitin sulfate (looks like spines growing off of core protein)
Hyaluronan (main molecule that has core proteins and link proteins attached to it)
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11
Q

Basal lamina

A

Connects epithelial cells to the extracellular matrix

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12
Q

Cadherins

A

Link like cells together

Requires calcium to adhere molecules

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13
Q

e-Cadherins

A

Link epithelial cells

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14
Q

Tight junctions

A

Form a seal between cells: barrier for molecules
Give cells polarity
Proteins: claudin and occludin (interlock adjacent cells)

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15
Q

Adhesive junctions

A

Adherens junctions and desmosomes

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16
Q

Adherens junctions

A

Join an actin bundle in one cell to another actin bundle in an adjacent cell
Actin and cadherin: adhesion belt
Contraction

17
Q

Desmosomes

A

Join intermediate filaments in one cell to intermediate filaments in another cell
Intermediate filaments and cadherins

18
Q

Hemidesmosomes

A

Cell to extracellular matrix junction
Anchor intermediate filaments in a cell to the basal lamina
Integrins span the membrane (inside cell- linked to keratin, an intermediate filament; outside cell- linked to laminin and collagen

19
Q

Gap junctions

A

Form channels that allow small water-soluble molecules to pass from cell to cell
Linkage of cytoplasm and adjacent cells
Connexon (protein that composes these) forms a hollow channel between adjacent cells

Cell Bio (15 decks)

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