Translation Flashcards

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1
Q

Open reading frame

A

The codons of an mRNA that are read sequentially (5’ to 3’) to specify amino acids

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2
Q

Triplet code

A

Each mRNA codon consists of 3 nucleotides

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3
Q

Continuous

A

The mRNA is read 3 nucleotides at a time without skipping any

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4
Q

Nonoverlapping

A

The mRNA is read in successive groups of 3 nucleotides

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5
Q

Redundant/degenerate

A

More than 1 codon occurs for each amino acid (3rd nucleotide might be different)
Allows for protection against mutation

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6
Q

Unambiguous

A

1 codon specifies 1 amino acid

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7
Q

Start and stop signal

A

Call for beginning and end of an open reading frame
AUG= start (codes for met)
Stop= nonsense codon (doesn’t code for amino acid)

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8
Q

Codon bias

A

Tendency of an organism to use a certain codon for 1 amino acid more than other codons

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9
Q

Wobble

A

Base pairing between tRNA anticodon and mRNA codon doesn’t necessarily follow complementary base pairing rules at the 3rd nucleotide
Reason: energetic favorability

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10
Q

Peptide bond

A

Covalent bond between amino acids

Formation catalyzed by ribosomes

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11
Q

R groups

A

Variable region of amino acids

Determine how polypeptide will fold and thus function

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12
Q

Nonpolar hydrophobic amino acids

A

Val Ile Pro Phe Ala Leu Met Gly Trp

VIP PALM GT

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13
Q

Polar hydrophilic amino acids

A

Cys Thr Ser Tyr Asn Gln

Come Taste STAG

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14
Q

Positively charged polar amino acids

A

His Arg Lys

Shallow HAL is a positive movie

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15
Q

Negatively charged polar amino acids

A

Asp, Glu

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16
Q

Polyribosomes (polysomes)

A

Multiple ribosomes translating same RNA concurrently

Occur in both proks and euks

17
Q

Simultaneous transcription and translation

A

Occurs in proks only