Population Genetics Flashcards

1
Q

Gene pool

A

All of the alleles in a population

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2
Q

Calculating genotypic frequency

A

Genotypic frequency= total # of individuals with specific genotype/ total # of individuals in population

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3
Q

Calculating allelic frequency

A

Allelic frequency= # of a specific allele/ total # of all alleles

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4
Q

p and q

A

p= frequency of dominant allele (B)
q= frequency of recessive allele (b)
p+q=1

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5
Q

Hardy-Weinberg law

A

Method scientists use to calculate allelic and genotypic frequencies in the absence of evolutionary forces: determine genetic variation in a population

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6
Q

Genetic equilibrium

A
Assumption for Hardy-Weinberg law: allelic frequencies don't change over time
No migration
Infinitely large population
Random mating
No mutation
No natural selection
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7
Q

Hardy-Weinberg equation

A

p^2 + 2pq + q^2 = 1
p^2= f(AA)
2pq= f(Aa)
q^2= f(aa)

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8
Q

Cline

A

Gradient for allele frequencies that changes in a systematic way according to the physical attributes of the environment

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9
Q

Polymorphisms

A

Changes in DNA sequence between individuals

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10
Q

How polymorphisms are found

A

Visualized by microscopy of chromosomes
Repeats are found by observing size differences between DNA sequences using gel electrophoresis
RFLP analysis to identify SNPs (single nucleotide polymorphisms)

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11
Q

RFLP analysis

A

Method of identifying SNPs

SNP changes restriction enzyme site: different number of fragments observed in gel electrophoresis

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12
Q

Fitness

A

Relative reproductive ability of a genotype

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13
Q

Natural selection

A

Frequency of alleles that confer survival and reproduction increases in the population

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14
Q

Positive assortative mating

A

Organisms mate with others that are similar to them

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15
Q

Negative assortative mating

A

Organisms mate with others that are different from them

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16
Q

Genetic drift

A

Changes in allele frequencies due to random sampling
Reduces genetic diversity
Ex- settlers killing off millions of bison on the Great Plains

17
Q

Bottleneck effect

A

Population is drastically reduced in number, reducing genetic diversity
Not due to anything that would reduce selectively, like certain diseases

18
Q

Founder effect

A

Population is established from a small number of breeding individuals
Reduced genetic diversity

19
Q

Immigration’s effect on alleles

A

Introduces new alleles

20
Q

Emigration’s effect on alleles

A

Takes away alleles

21
Q

Gene flow

A

An individual migrates and contributes its alleles to the gene pool of the new population