Population Genetics Flashcards
Gene pool
All of the alleles in a population
Calculating genotypic frequency
Genotypic frequency= total # of individuals with specific genotype/ total # of individuals in population
Calculating allelic frequency
Allelic frequency= # of a specific allele/ total # of all alleles
p and q
p= frequency of dominant allele (B)
q= frequency of recessive allele (b)
p+q=1
Hardy-Weinberg law
Method scientists use to calculate allelic and genotypic frequencies in the absence of evolutionary forces: determine genetic variation in a population
Genetic equilibrium
Assumption for Hardy-Weinberg law: allelic frequencies don't change over time No migration Infinitely large population Random mating No mutation No natural selection
Hardy-Weinberg equation
p^2 + 2pq + q^2 = 1
p^2= f(AA)
2pq= f(Aa)
q^2= f(aa)
Cline
Gradient for allele frequencies that changes in a systematic way according to the physical attributes of the environment
Polymorphisms
Changes in DNA sequence between individuals
How polymorphisms are found
Visualized by microscopy of chromosomes
Repeats are found by observing size differences between DNA sequences using gel electrophoresis
RFLP analysis to identify SNPs (single nucleotide polymorphisms)
RFLP analysis
Method of identifying SNPs
SNP changes restriction enzyme site: different number of fragments observed in gel electrophoresis
Fitness
Relative reproductive ability of a genotype
Natural selection
Frequency of alleles that confer survival and reproduction increases in the population
Positive assortative mating
Organisms mate with others that are similar to them
Negative assortative mating
Organisms mate with others that are different from them