Mendel and Meiosis Flashcards
Cell cycle
2 phases: M phase (mitotic phase; division) and interphase (replication of chromosomes in preparation for cell division)
3 parts of interphase
G1, S (DNA replication), G2
Gametogenesis
Formation of haploid gametes in animals
Sporogenesis
Formation of haploid spores in plants and fungi
Prophase I
Chromosomes condense
Synapsis: homologous chromosomes line up and connect to each other by a synaptonemal complex
Crossing over
Metaphase I
Chromosomes line up by homologous pairs along the metaphase plate
Random lineup of pairs
Anaphase I
Each pair of homologous chromosomes separates
Telophase I
Two haploid cells form
Each chromosome consists of 2 sister chromatids
Prophase II
Same as regular prophase (chromosomes condense, mitotic spindle starts to form, etc.)
Metaphase II
Sister chromatids align
Anaphase II
Sister chromatids separate
Telophase II
4 unique haploid daughter cells form
Crossing over
Occurs during prophase I
Genetic recombination: mixing of alleles, creating new allelic combinations in chromatids
Chiasma
Cross-like structure where crossing over occurs
Tetrad
Homologous pair of chromosomes each with 2 sister chromatids
Law of Segregation
In meiosis I, homologous chromosomes end up at one pole or the other at random
Law of Independent Assortment
In meiosis I, chromosomes don’t influence each other’s segregation
Testcross
Cross of unknown genotype (homozygous dominant or heterozygous) with homozygous recessive individual
Allows for determination of unknown genotype
Product rule
The probability of 2 or more independent events occurring simultaneously is the product of their individual probabilities
Sum rule
The probability of either one of several independent, mutually exclusive events is the sum of their individual probabilities
Binomial theorem
Probability that a situation will occur when there are multiple ways to get a combination
Probability= [(n!)/(s!t!)] (a^s) (b^t)
n= total # of events, a= probability of outcome #1, b=probability of outcome #2, s=# of times outcome #1 occurs, t=# of times outcome #2 occurs
of different gametes that can be formed from a genotype
# of gametes= 2^n n=# of heterozygous gene pairs