Transgender Medicine Flashcards

1
Q

What is the definition of transsexualism?

A

A desire to live and be accepted as a member of the opposite sex, usually accompanied by a sense of discomfort with or inappropriateness of one’s anatomical sex and a wish to have treatment to make one’s body as congruent as possible to one’s preferred sex

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2
Q

What is the definition of dual-role transvestism?

A

The wearing of clothes of the opposite sex for part of the individual’s existence in order to enjoy the temporary experience of membership of the opposite sex but without any desire for a more permanent sex change or associated surgical reassignment and without sexual excitement accompanying the cross-dressing

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3
Q

What is the definition of fetishistic transvestism?

A

The wearing of clothes of the opposite sex principally to obtain sexual excitement and to create the appearance of a person of the opposite sex - it has a clear association with sexual arousal and a strong desire to remove the clothing once orgasm occurs and sexual arousal declines

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4
Q

What is gender identity disorder of childhood?

A

A disorder with usually manifests during early childhood and always well before puberty that is characterised by persistent and intense distress about the assigned sex, together with a desire to be or an insistence that one is of the other sex

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5
Q

Before undergoing hormonal treatment, transgender patients may undergo fertility preservation. What does this involve?

A

The collection and storage of either oocytes or sperm

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6
Q

What are the qualifying criteria for hormone therapy in transgender patients?

A

Well-documented gender dysphoria
Capacity to make a fully informed decision and consent to treatment
Age of majority
Significant medical/mental health concerns reasonably well-controlled

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7
Q

GnRH analogues are given to transgender patients in order to…?

A

Suspend pubertal development of secondary sex characteristics

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8
Q

What hormonal treatment suspends facial hair growth, voice changes, Adam’s apple formation and male skeletal, facial and musculature changes in trans patients?

A

AMAB

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9
Q

What hormonal treatment stops periods and halts breast growth in trans patients?

A

AFAB

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10
Q

At what age can surgery be undertaken for transgender patients?

A

18

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11
Q

What drug is given as the initial hormonal treatment for transmen?

A

Sustanon

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12
Q

If testosterone alone does not suppress menstruation, what other drugs can be given to transmen?

A

Deep provera

GnRH analogues such as triptorelin

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13
Q

If a transman is sexually active with a male partner then testosterone alone is sufficient for contraception. T/F?

A

False - progesterone is required by deep proverb, implant or IUS

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14
Q

What effect does testosterone hormonal treatment have an transmen?

A
Lowers voice
Increases facial and body hair growth
Increases muscle bulk
Amenorrhea
Clotoromegaly
Increased libido
Agression
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15
Q

What side effects can hormonal treatments have on transmen?

A
Polycythaemia
Liver dysfunction
Increased risk of cardiovascular disease
Increased weight
Diabetes
Mental health disturbances
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16
Q

Oestradiol valerate is taken as a hormonal treatment for transwomen at what dose initially?

A

1-2mg

17
Q

What drugs can be used by transwomen as anti-androgens?

A

Triptorelin
Cyproterone acetate
spironolactone

18
Q

What are the effects of hormonal treatment on transwomen?

A
Breast growth
Softer skin
Less facial and body hair
Fat redistribution to hips
Increased emotions
19
Q

What are the potential side effects of hormonal treatment for transwomen?

A

Increased risk for venous thromboembolism and breast cancer
increased weight
increased blood pressure
migraines

20
Q

What surgeries can be undertaken by transmen?

A
bilateral mastectomy
hysterectomy
oophorectomy
metoidioplasty
phalloplasty
21
Q

What are the potential adverse effects of surgery for transmen?

A
Neo-urethral stenosis
Urethral fistulas
Dislodgement
Erectile cylinders
Mechanical failure of erectile mechanism
22
Q

Do transmen need to be on the SCCRS for cervical smears?

A

Only if they have not had a hysterectomy

23
Q

What surgeries can be undertaken by transwomen?

A
Thyroid chondroplasty
Penectomy
Orchidectomy
Clitiroplasty
Vulvoplasty
Penile inversion Vaginoplasty
Colovaginoplasty
Breast augmentation
24
Q

What are the potential adverse effects of surgery for transwomen?

A
Urinary spraying
Increased risk of UTIs
Granulation tissue formation
Neovaginal hair growth
Neovaginal structure
Vascular occlusion of arterial supply to neoclitoris
Ongoing need for dilation
25
Q

Are transwomen given screening tests for cervical cancer prostate cancer or breast cancer?

A

Only for prostate and breast cancer

26
Q

What is the normal hormone level of testosterone in transmen?

A

8-15nmol/l

27
Q

What is the normal hormone level of estradiol in transwomen?

A

200-600pmol/l