Transfusions Flashcards
What are the 5 types of transfusions
- Homologous (Allogenic)
- Autologous
- Blood salvage
- Directed donor
- Artificial blood
What is the 5 criteria for blood donation
- healthy
- older than 17
- 110lbs and above
- Hgb 12.5g/dl for women and 13.5 for men
- <99.6 temp
How long can red blood cell donations be stored and at what temp?
42 days at 4* celsius
How long can platelet donations be stored and at what temp?
5 days at room temp
How long can fresh frozen plasma be stored and at what temp?
1 year and frozen
What is the normal lab values for hematocrit and hemoglobin including ratio?
HCT: 35-45% (males slightly higher)
HGB: 12-15 gm/dl (males slightly higher)
HCT : HGB = 3 : 1
What is the normal lab values for platelets?
150,000 - 350,000
What is the normal prothrombin time (PT) lab values?
9-11 seconds
What is the normal international normalised ratio (INR) lab values?
1
What is the normal partial thromboplastin time (PTT) lab value?
25-35 seconds
What are the two therapeutic effects of pRBC transfusion?
Increases O2 carrying capacity of blood and replaces blood loss
What are the indications (including lab values) of pRBC transfusion?
Active bleed
HCT <25% OR HGB <8 & symptomatic
What is the therapeutic effect of platelet transfusion?
increased thrombocytes (controls bleeding by replacing platelets)
What are the indications of platelet transfusion?
PLT < 50,000 and active bleed, or
PLT < 20,000
What is the therapeutic effect of fresh frozen plasma transfusion?
increased clotting factors
What are the indications for fresh frozen plasma transfusion?
INR >1.5 or PT>15 seconds or PTT>45 seconds
What are the transfusion - disease contamination risks?
HIV, HCV etc e.g. zika virus?
What are the 5reaction risk complications of transfusions?
Febrile: (temp increase >2deg)
Allergies: flushing, pruritis etc
Hemolytic: fever/chills, back pain, dark urine
Fluid overload
Sepsis
What are the S/Sx of needing pRBC transfusion?
fatigue, weakness, tachycardia, pallor, low O2 sat, active bleed
Explain type & cross procedure?
Type: blood type & Rh factor, expiration, client ID
Cross match: indirect coombs - want a negative
How long is transfusion consent good for?
if outpatient - 1 year
if inpatient - duration of stay
How may RN’s are required to sign out blood transfusion at bedside?
2
What gauge IV is used for blood transfusion?
19 or 20 gauge is preferred
What filtration is required for blood transfusion?
blood must be filtered using Y tubing with filter
What is the timeframe for blood transfusion?
0-4 hours but generally is around 2 hours
Explain key points for monitoring blood transfusion?
Start transfusion slow and stay for first 15 minutes
Vitals: take baseline vitals and at end
Temp: at 15 minutes (and ask about symptoms), then complete every hour
What are the rules about blood transfusion delegation?
What are the expected results for pRBC transfusion?
Increase of 3% HCT and 1gm HGB for each unit of blood
When is blood drawn after blood transfusion to check results?
after 2-4 hours NOT earlier
What happens if patient wants to go off unit during blood transfusion?
What happens if blood transfusion pt only has one IV line but needs PCA and IV antibiotic?
What happens if RN receives a call that blood transfusion pt needs MRI?
How is a reaction to blood transfusion recognised?
fever: increase >2 deg (most reliable sign)
itching, rash, flushed face/chest, chest pain, tachy, hypotension
Nursing intervention for blood transfusion reaction?
- STOP transfusion
- take down blood & tubing and replace with NS and new tubing
- blood sent back to blood bank
- call MD
- monitor VS
- direct coombs test (checks for hemolytic reaction)
What is the expected lab response to platelet transfusion?
Increase of 5000 to 10,000 per unit of platelets (normally multiple units are given)
What is the expected lab response to plasma transfusion?
INR: decrease (move towards normal)
PT: will decrease (clot quicker)
PTT: will decrease (clot quicker)
Nursing interventions to speed up a slow transfusion?
- hang blood higher
- take blood down and gently agitate
- flush IV and restart blood
- use a pressure cuff
Nursing interventions to minimise need for transfusion?
minimise bleeding risk: bedrest, bledsoe brace, no phlebotomy
rebuild blood: iron/folate/B12, epoiten alpha