Transfusion consideration for the Fetus/newborn

Question 1

Fetus

Answer 1

unborn
relies on mother
placenta and cord
diff to collect speimen

Question 2

Newborn

Answer 2

infant - 4mos

ab developing
no maternal waste

heel/cord blood

Question 3

What do you do on Rh negative babies

Answer 3

only forwards type, weak D test

Question 4

Types of HDFN by blood groups

ABO

Answer 4

ABO most common

O mom A,B baby

least severe

Question 5

HDFN

Rh (D)

Answer 5

least common most severe

Question 6

Other HDFN causes

Answer 6

K + c common

Question 7

Hydrops Fetalis
fetal death around?

fetal screen shows?

hepa
ed
as
eff

Answer 7

Fetal death, 18-20 wks

Fetal screen: senst rbc hemolysis

hepatosplenomegaly
edema, ascities, effusions

Question 8

severity of disease in utero

Answer 8

ultrasonography
amniosentesis
cordosentises

Question 9

Kernicterus

Answer 9

> 18mg/dl of bilirubin

jaundice
billirubin in brain
<4 days

1.) phototherapy
2.) IVIG
3.) exchange transusion double vol

Question 10

Selecting for blood for transfusion

Answer 10

O, AB compatitble Rh negative

rbcs <7 days

CMV negative/ LRBCS
irradiated

Question 11

PLT selections

Answer 11

<50,000
FFP

Question 12

Blood vol and babies
cant tolerate?

what is required?

suscept?

toxicity?

Answer 12

cannot tolerate >10% blood loss

blood warmers required

susc to graft vs host

Toxicity: K+, Ca+, H

Question 13

ECMO

Answer 13

increased CO2
cardiac surgery revocery, aspiration syndrome

1-2 units + 1FFP

Question 14

Polycythemia

Answer 14

HCT >65% too viscus

whole blood

Cordblood workup = type/screen