Transfusion

Question 1

Within what time limit must red cells be transfused after leaving the controlled storage?

Answer 1

4 hrs

Question 2

Within what time limit must platelets be transfused after leaving the controlled storage?

Answer 2

1 hr

Question 3

Within what time limit must fresh frozen plasma be transfused after leaving the controlled storage?

Answer 3

4 hrs

Question 4

Naturally occurring ABO antibodies are primarily what type?

Answer 4

IgM (pentameric structure)

Question 5

Inheritance of ABO blood group occurs on which chromosome?

Answer 5

chromosome 9

Question 6

Inheritance of Rh (D) blood group occurs on which chromosome?

Answer 6

1

Question 7

Describe the steps of the process of giving a red cell transfusion.

Answer 7

1. Obtain blood sample from patient - accurate ID is critical
2. Complete request form:
   patient ID, location, indication for transfusion
   time required, number of units required,
   previous transfusion history, your name (legible)
   and contact number
3. Send sample and form to the transfusion lab
   (if outwith normal hours, contact the MLSO)
4. Prepare patient for transfusion

Question 8

What is Acute (Immediate) Haemolytic Transfusion Reaction usually associated with ?

Answer 8

the naturally-occurring IgM antibodies of the ABO system

Question 9

Which factor activates the kinin system?

Answer 9

Activated factor XII

Question 10

What actions should be take if a transfusion reaction occurs?

Answer 10

stop transfusion
start iv fluids to maintain BP and urine output
obtain blood samples

Question 11

What causes urticarial reactions?

Answer 11

IgE response to infused plasma proteins

Question 12

In whom does circulatory overload occur, and what does it cause?

Answer 12

Pulmonary oedema

Elderly, and those with CCF, especially at risk