Introduction

Question 1

What term describes the production of red blood cells?

Answer 1

haemopoiesis

Question 2

What is the site of haemopoiesis in the first two months of pregnancy?

Answer 2

yolk sac then liver

Question 3

What is the site of haemopoiesis in the 3rd to 5th month of pregnancy?

Answer 3

spleen

Question 4

What is the site of haemopoiesis at birth?

Answer 4

bone marrow, liver and spleen is needed

Question 5

What is the site of haemopoiesis from birth to maturity?

Answer 5

bone marrow active sites decrease, but retain ability

Question 6

What is the site of haemopoiesis in adults?

Answer 6

ribs, sternum, skull, pelvis, proximal end of femur

Question 7

What is the stage before a mature red blood cell?

Answer 7

reticulocyte

Question 8

What is the term for Platelets forming on the periphery of this megakaryocyte?

Answer 8

budding

Question 9

Name the granulocytes.

Answer 9

Eosinophils
Basophils
Neutrophils

Question 10

What is special about granulocytes?

Answer 10

Contain granules that are easily visible on light microscopy

Question 11

Structure of neutrophils?

Answer 11

Segmented nucleus (polymorph)

Question 12

Why do neutrophils stain with a lilac hue?

Answer 12

the cytoplasm

Question 13

Describe the structure and colour of eosinophils.

Answer 13

Usually bi-lobed

Bright orange/red granules

Question 14

Describe colour and size of basophils.

Answer 14

Large deep purple granules obscuring nucleus

Question 15

Are basophils large in number?

Answer 15

no

Question 16

What circulate for a week and enter tissues to become macrophages?

Answer 16

monocytes

Question 17

Describe the mature and activated forms of lymphocytes.

Answer 17

Mature – small with condensed nucleus and rim of cytoplasm
Activated (often called atypical) – large with plentiful blue cytoplasm extending round neighbouring red cells on the film, nucleus more ‘open’ structure

Question 18

What are common sites for bone marrow aspiration and biopsy?

Answer 18

posterior iliac crests