Introduction Flashcards
What term describes the production of red blood cells?
haemopoiesis
What is the site of haemopoiesis in the first two months of pregnancy?
yolk sac then liver
What is the site of haemopoiesis in the 3rd to 5th month of pregnancy?
spleen
What is the site of haemopoiesis at birth?
bone marrow, liver and spleen is needed
What is the site of haemopoiesis from birth to maturity?
bone marrow active sites decrease, but retain ability
What is the site of haemopoiesis in adults?
ribs, sternum, skull, pelvis, proximal end of femur
What is the stage before a mature red blood cell?
reticulocyte
What is the term for Platelets forming on the periphery of this megakaryocyte?
budding
Name the granulocytes.
Eosinophils
Basophils
Neutrophils
What is special about granulocytes?
Contain granules that are easily visible on light microscopy
Structure of neutrophils?
Segmented nucleus (polymorph)
Why do neutrophils stain with a lilac hue?
the cytoplasm
Describe the structure and colour of eosinophils.
Usually bi-lobed
Bright orange/red granules
Describe colour and size of basophils.
Large deep purple granules obscuring nucleus
Are basophils large in number?
no
What circulate for a week and enter tissues to become macrophages?
monocytes
Describe the mature and activated forms of lymphocytes.
Mature – small with condensed nucleus and rim of cytoplasm
Activated (often called atypical) – large with plentiful blue cytoplasm extending round neighbouring red cells on the film, nucleus more ‘open’ structure
What are common sites for bone marrow aspiration and biopsy?
posterior iliac crests
