transcription Flashcards
Ribosomal RNA (rRNA)
80%. Form the core of ribosome and catalyze protein synthesis
Transfer RNA (tRNA)
15%. Form adaptors that select and hold amino acids during protein synthesis
Messenger RNA (mRNA)
1-5%. Short lived, directly involved in protein synthesis. Coding RNAs.
Small nuclear RNA (snRNA)
direct the splicing of pre-mRNA to form mRNA (remove introns)
Small interfering RNA (siRNA)
regulate eukaryotic gene expression by degrading select mRNA
Micro RNA (miRNA)
regulate gene expression by blocking translation of selective mRNA
RNA polymerase 1
rRNA
RNA polymerase 2
mRNA
RNA polymerase 3
tRNA
Aberrant methylation. Fragile X Mental Retardation (FMR1)
FMR1 gene encodes for a protein of neurological function. expansion of CGG repeat makes it susceptible to methylation of cytosine. Turns of transcription and gene becomes silent