tissue renewal and repair

Question 1

four functional classes of cell junctions

Answer 1

anchoring junctions, occluding junctions, channel-forming junctions, signal-relaying junctions

Question 2

anchoring junctions

Answer 2

cell-cell adhesions and cell-matrix adhesion, and are connected to cytoskeletal filaments inside the cell

Question 3

channel-forming junctions

Answer 3

create passageways for small molecules and ions to pass from cell to cell

Question 4

homotypic

Answer 4

adhesion b/w similar cell types

Question 5

heterotypic

Answer 5

adhesion b/w varying cell types

Question 6

classical cadherins

Answer 6

Form adheren junctions. Important in signaling. E-cadherin, N-cadherin, VE-cadherin, P-cadherin

Question 7

non-classical cadherins

Answer 7

form desmosome junctions. desmocollins and desmogleins proteins involved. protocadherins (neuronal plasticity)

Question 8

E-cadherin

Answer 8

epithelial cells and fibroblasts

Question 9

N-cadherin

Answer 9

muscle, nerve, lens, cells, fibroblasts

Question 10

VE- cadherin

Answer 10

endothelial cell

Question 11

P-cadherin

Answer 11

placenta and epidermis

Question 12

occluding junctions

Answer 12

seal gaps between epithelial cells so as to make the epithelial sheet into an impermeable barrier

Question 13

tight junction proteins

Answer 13

claudin and occludin

Question 14

polarity protein complexes control polarization processes with tight junctions

Answer 14

Par (partitioning defective), Crumbs and Scribble

Question 15

missense mutation in desmocollin-2 associated with

Answer 15

ARVC- arrhythmogenic right ventricular cardiomiopathy

Question 16

actin filament elongating complex

Answer 16

ARP

Question 17

nucleation of microtubule growth complex

Answer 17

gama-TuRC

Question 18

ehlers-danlos VI

Answer 18

defective enzyme (prolyl or lysyl hydroxylase)

Question 19

scurvy

Answer 19

loss of cofactor (abscrobate, Fe2+)

Question 20

type 1 collagen

Answer 20

bone, skin, tendon, cornea

Question 21

type IV collagen

Answer 21

basal lamina

Question 22

integrin alpha 2 beta 1 binds to

Answer 22

collagen

Question 23

integrin alpha v beta 6 binds to

Answer 23

fibronectin

Question 24

marfan’s syndrome

Answer 24

mutated fibrillin in elastin. Abe lincoln had it. tall and lanky