Trace Minerals Flashcards

1
Q

Trace Minerals

A

Microminerals; Nutrients needed by body in very small amounts (less than one-hundreth of 1% of total body weight); Concentrations in body highly regulated, Normal body function necessitates optimal range, Toxicity at intakes far above estimated

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2
Q

Trace Mineral Content of Food

A

Dependent upon composition of soil and water, Processing of foods, Many dietary components and factors within body affect bioavailability

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3
Q

Trace Minerals Dietary Need for Body

A

1 ppm or less

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4
Q

Examples of Trace Minerals

A

Iron, Zinc, Selenium, Iodine, Fluoride, Copper, Manganese, Chromium, Molybdenum

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5
Q

Iron

A

Dietary choices lead to not sufficient intake, Others consume too much iron; Transport of oxygen to tissues, Energy production, Maintenance of immunity, Synthesis of amino acids, hormones and neurotransmitters

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6
Q

Iron Function

A

Proteins: Hemoglobin (RBC) and Myoglobin (Muscle cells)

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7
Q

Hemoglobin Role

A

Oxygen-transferring protein of RBC that transports oxygen from lungs to body tissues, Hemoglobin accounts 80% of body’s iron

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8
Q

Heme VS Nonheme

A

Heme-Animal flesh

Nonheme-Plants

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9
Q

Factors that affect Iron Absorption

A

Increase: Gastric acid, Heme iron in food, High body demand for RBC (blood loss, high altitude, physical training, pregnancy), Low body stores of iron, Meat protein factor, Vitamin C
Decrease: Phytic acid, Oxalic acid, Polyphenols (Coffee, Red Wine), Full body stores, Excess minerals, Reduced gastric acid output, Antacids

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10
Q

RDA Iron for Adults

A

Males: 8mg/day
Females (19-50): 18mg/day
Females (51+): 8mg/day

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11
Q

Food Sources of Iron

A

Red meat, Fish, Poultry, Eggs, Legumes, Dry Fruits

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12
Q

Meat Fish Poultry (MFP) Factor

A

Associated with digestion of meat, fish, poultry and enhances absorption of iron

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13
Q

Iron Absorption

A

Varies with individuals health, life stage and iron needs/status, Varies 2-35% with average 18%, Enhanced with higher needs like pregnancy and other life stages with rapid growth

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14
Q

Anemia

A

Severe depletion of iron stores that results in low hemoglobin and small, pale, red blood cells (microcytic, hypochromic)

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15
Q

Nutrient Deficient Anemia

A

Iron, Cobalamin (Vitamin B12), Protein, Other Vitamins (B6)

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16
Q

Other Conditions that lead to Anemia

A

Hemorrhage, Genetic abnormality, Chronic disease states (Cancer, Hypothyroidism, Cardiovascular disease), Drug toxicity

17
Q

Populations Vulnerable to Iron Deficiency

A

Infants, Adolescents, Women in childbearing years and Pregnant women

18
Q

Symptoms of Iron-Deficiency Anemia

A

Fatigue, Anorexia, Reduced capacity to work, Poor immune response, Impaired cognition function

19
Q

Treatment of Iron-Deficiency Anemia

A

Depends upon underlying cause and severity, Dietary modifications, Supplements, Appropriate medications, Severe iron deficiency anemia require blood transfusion, iron injections, intravenous iron therapy and treatment in hospital

20
Q

Toxicity

A

10% population in US is positive iron balance, 1% iron overload; Two types- Hemochromatosis and Hemosiderosis; Iron overload with heart disease (oxidized LDL)

21
Q

Zinc

A

Concentrated in bone, liver, kidney and muscle tissues; Amount in body is 1.5-2.5g

22
Q

Zinc functions

A

Cofactor for more than 100 enzymes, Cellular growth, Bone formation, Cell mediated immunity, Part of insulin, Thyroid function, Behavior and learning

23
Q

RDA for Zinc

A

Males (19-50): 15mg/day

Females (19-50): 12mg/day

24
Q

Zinc Deficiency

A

1960-Children and adolescent boys in Egypt, Iran and Turkey; Rapid growth phases associated with higher zinc

25
Q

Populations Vulnerable to Zinc Deficiency

A

Alcoholics, Trauma, Lacto-Vegetarians, Pregnant women, Elderly, Post-surgical patients

26
Q

Zinc Deficiency Symptoms

A

Growth retardation, Skeletal abnormalities, Defective collagen synthesis, Poor wound healing, Delayed sexual maturation (children), Hypogeusia (diminished taste)

27
Q

Significant Food Sources of Zinc

A

Protein-containing foods- Meat, fish, poultry; Whole grains, Vegetables

28
Q

Metabolism of Zinc

A

Zinc is absorbed by intestinal cells, Attached to albumin and transferrin and circulated in blood, Excess stored in liver as metallothionein, Pancreas uses zinc to make digestive enzymes, Some losses in urine, skin, blood and semen

29
Q

Selenium

A

Antioxidant, Cofactor for Glutathione Peroxidase; Selenium-poor soil correlates with cancer incidence

30
Q

RDA Selenium for Adults

A

Adults: 55microg/day

Upper level: 100microg/day

31
Q

Selenium Deficiency

A

Keshan disease, Kashin-Beck’s disease

32
Q

Keshan Disease

A

Cardiomyopathy, Congestive heart failure, Necrosis of heart tissue

33
Q

Kashin-Beck’s Disease

A

Disorder of bones and joints of hands, fingers, elbows, knees and ankles in children and adolescents; Occurs due to necrosis (death) of growth plates of bones and joint cartilage