TRACE ELEMENTS Flashcards
Enhances insulin action; for glucose and lipid
-deficiency: type 2 DM, insulin resistance, hyperlipidemia
Chromium
-hemoglobin synthesis, component of Vitamin B12
-Deficiency: Pernicious anemia,
Cobalt
-cellular respiration; collagen synthesis
-Deficiency: Menkes ‘kinky hair’ syndrome
-Toxicity: interferes with absorption of iron and zinc
Copper
-prevents dental carriers
-Deficiency: Dental carriers
Fluorine
Thyroid hormone synthesis
-Deficiency: Goiter, cretinism, myxedema
-Toxicity: Thyrotoxicosis
Iodine
-Oxygen transport , component of hemoglobin
-Deficiency: Anemia
-Toxicity : Hemochromatosis
Iron
the most important essential trace element
Iron
Bone and connective tissue function
-Deficiency: skeletal defects
-Toxicity: Parkinson’s disease , lacura mangatica (miners)
Manganese
DNA metabolism
-Deficiency: Growth depression, cretinism, goiter
Molybdenum
Prevents oxidative damage of lipids
-Deficiency: keshan disease
-Toxicity: hair and nail loss, liver failure
Selenium
protein synthesis
-Deficiency: Acrodermatitis, enteropathica, growth deficiency, immune deficiency, infertility, delayed wound healing , osteoporosis
Zinc
most commonly used instrumentation for trace and toxic metal analysis
Atomic absorption spectrometer
Transport iron (in the ferric or Fe3+ state) throughout the body.
Apotransferrin
