toxins + antidotes Flashcards
acetominophen
N-acetylcysteine (replenishes glutathione)
salicylates
NAHCO3 (alkalinizes urine); dialysis
amphetamines (basic)
NH4Cl (acidify urine)
acetylcholineterase inhibitors, organophosphates
atropine, pralidoxime
antimuscarininc, anticholinergic agents
physostigmine salicylate, control hyperthermia
B-blockers
glucagon (acts on GPCR, inc. cAMP in cardiac myocytes)
digitalis
normalize K+, lidocaine, anti-dig Fab fragments, Mg2+
iron
deferoxamine, deferasirox
lead
CaEDTA, dimercaprol, succimer, penicillamine
mercury, arsenic, gold
dimercaprol, succimer
copper, arsenic, gold
penicillamine
cyanide
nitrate+thiosulfate, hydroxocobalamin
methemoglobin
methylene blue, vitamin C
carbon monoxide
100% oxygen, hyperbaric oxygen
methanol, ethylene glycol (antifreeze)
fomepizole>ethanol, dialysis