autoantibodies and their disorders Flashcards

1
Q

anti-nuclear antibodies

A

SLE, nonspecific

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2
Q

Anti-dsDNA, anti-Smith

A

SLE

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3
Q

Anti-histone

A

drug-induced lupus

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4
Q

Rheumatoid factor, anti-CCP

A

Rheumatoid arthritis

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5
Q

Anticentromere

A

Scleroderma (CREST syndrome)

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6
Q

Anti-Scl70 (anti-DNA topoisomerase I)

A

diffuse scleroderma

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7
Q

IgA antiendomysial, IgA anti-tissue transglutaminase

A

celiac disease

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8
Q

Anti-basement membrane

A

goodpasture’s syndrome

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9
Q

Anti-desmoglein

A

pemphigus vulgaris

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10
Q

Antimicrosomal, antithyroglobuin

A

Hashimoto’s thyroiditis

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11
Q

Anti-Jo1, Anti-SRP, anti-Mi2

A

polymyositis, dermatomyositis

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12
Q

Anti-SSA

A

sjogren’s syndrome

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13
Q

anti-SSB

A

sjogrens syndrome

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14
Q

anti-U1 RNP

A

mixed CT disease

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15
Q

anti-smooth muscle

A

autoimmune hepatitis

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16
Q

anti-glutamate decarboxylase

A

type 1 DM

17
Q

c-ANCA

A

granulomatosis w/ polyangiitis (Wegeners)

18
Q

p-ANCA

A

microscopic polyangiitis, Churg-Strauss syndrome