Toxin Antidotes Flashcards
Acetaminophen
N-acetylcystine
Anticholinesterases (organophosphates)
Atropine + pralidoxime
Amphetamines
Ammonium chloride (acidify urine)
Antimuscarinic, anticholinergic agents
Physostigmine and control hyperthermia
Arsenic
Dimercaprol + succimer
Benzodiazepines
Flumazenil
Beta-blockers
Saline + atropine + glucagon
Carbon monoxide
100% O2, hyperbaric O2
Copper
Penicillamine, trientine
Cyanide
Nitrite + thiosulfate, hydroxycobalamin
Digoxin
Anti-Dig Fab fragments, K+ and Mg++ to normalize if needed
Gold
Dimercaprol, succimer, penicillamine
Heparin
Protamine sulfate
Iron
Deferoxamine, deferasirox, deferiprone
Lead
EDTA, dimercaprol, succimer, penicillamine
Mercury
Dimercaprol, succimer
Methanol, Ethylene glycohol
Fomepizole > ethanol, dialysis
Methemoglobin
Methylene blue, vitamin C
Opioids
Naloxone
Salicylates
Sodium bicarbonate, dialysis
TCAs
Sodium bicarbonate
Warfarin
Fresh frozen plasma, vitamin K
tPA, streptokinase
Aminocaproic acid
Theophylline
Beta blocker